ArticleJournal of pain research2022
Effects of Exercise-Induced Hypoalgesia at Different Aerobic Exercise Intensities in Healthy Young Adults.
Article in Journal of pain research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Aerobic Exercise Prescription for Pain Reduction in Fibromyalgia: A Systematic Review and Meta-Analysis.European journal of pain (London, England) · 2025Pooled it
- Acute Clinical Effects of Dual-Task Resistance Exercise on Muscle Endurance and Pressure Sensitivity in Patients With Carpal Tunnel Syndrome After Surgery.Musculoskeletal care · 2026Trial
- Impact of upper-limb aerobic exercise on the prevention of chronic postsurgical pain after total knee arthroplasty: a randomized controlled trial.BMC research notes · 2026Trial
- Effects of 4-Week Treadmill Running at Different Intensities on Exercise-Induced Hypoalgesia and Endogenous Pain Modulation in Healthy Individuals.Pain research & management · 2026Trial
- Hypoalgesic effects, safety, and feasibility of a 6-minute high-lung-volume static apnea intervention.The Korean journal of pain · 2026Article
- Virtual reality enhances affective valence and attentional dissociation during exercise but not exercise-induced hypoalgesia.Virtual reality · 2026Article
- Physical activity mediates the relationship between weight status and pain impacting daily activities.International journal of obesity (2005) · 2025Article
- How can Blood Flow Restriction Exercise be Utilised for the Management of Persistent Pain Following Complex Injuries in Military Personnel? A Narrative Review.Sports medicine - open · 2025Review
- Effects of three exercise interventions on inhibitory control in college students with internet addiction: a functional near-infrared spectroscopy study.Frontiers in psychology · 2025Article
- Impact of electrical muscle stimulation-induced muscle contractions on endogenous pain modulatory system: a quantitative sensory testing evaluation.BMC musculoskeletal disorders · 2024Article
- Article
- Effects of Apnea-Induced Hypoxia on Hypoalgesia in Healthy Subjects.Sports (Basel, Switzerland) · 2024Article
- Exercise induced hypoalgesia after a high intensity functional training: a randomized controlled crossover study.BMC sports science, medicine & rehabilitation · 2024Article
- Mirror Therapy Reduces Pain and Preserves Corticomotor Excitability in Human Experimental Skeletal Muscle Pain.Brain sciences · 2024Article
- The Role of Physical Exercise in Chronic Musculoskeletal Pain: Best Medicine-A Narrative Review.Healthcare (Basel, Switzerland) · 2024Review
- Examining Changes in Pain Sensitivity Following 8 Minutes of Cycling at Varying Exercise Intensities.International journal of exercise science · 2024Article
- Pathology of knee osteoarthritis pain: contribution of joint structural changes and pain sensitization to movement-evoked pain in knee osteoarthritis.Pain reports · 2024Article
- Exercise-induced hypoalgesia in healthy males is best explained by mechanisms selectively affecting deep-tissue pain sensitivity within exercising body parts.Neurobiology of pain (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Exercise-induced hypoalgesia (EIH) is a reduction in pain sensitivity that occurs following a single bout of exercise. However, little research has compared the EIH effects of exercise at different intensities, including low intensity, in the same participant. It is unclear as to which exercise intensities demonstrate EIH more effectively. The aim of this study was to examine and compare the effect of different intensities of exercise on pain sensitivity in the same participant. Methods: We included 73 healthy young adult volunteers (35 female and 38 male) in this experimental cross-over study. Each participant completed four experimental sessions of 30 min, consisting of aerobic exercise at 30% heart rate reserve (HRR), aerobic exercise at 50% HRR, aerobic exercise at 70% HRR, and quiet rest. EIH was assessed using the pressure pain threshold (PPT) and temporal summation of pain (TSP) in the quadriceps, biceps, and trapezius. Results: Low- and moderate-intensity exercise increased the multisegmental PPT and reduced TSP (all Conclusion: Our results show that not only moderate- and high-intensity exercise, but also low-intensity exercise can produce a hypoalgesic response.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.