ReviewFrontiers in neurology2022
The brain structure and function abnormalities of migraineurs: A systematic review and neuroimaging meta-analysis.
Review in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The cerebellum in migraine: a narrative review of anatomical, imaging, and clinical evidence.Frontiers in neurology · 2026Pooled it
- Meta-analysis of cortical thickness reduction in adult schizophrenia.Journal of psychiatry & neuroscience : JPNPooled it
- Observational
- Semantic Content of Visual Consequent Stimuli Modulates Audiovisual Learning in Migraine.Brain and behavior · 2026Article
- Normative structural MRI deviation factors summarize patient-level neuroanatomical heterogeneity across episodic and chronic migraine.The journal of headache and pain · 2026Article
- Migraine and menopause as converging factors in brain vulnerability: a hypothesis-driven perspective.The journal of headache and pain · 2026Review
- Abnormal structural connectivity-functional connectivity coupling beyond the cortex in patients with chronic migraine.The journal of headache and pain · 2026Article
- Neurocognitive Performance and Executive Functions Do Not Influence Conditioned Pain Modulation in Women with Migraine.Life (Basel, Switzerland) · 2025Article
- Cortical network dysfunction in migraine: linking genes, metabolism and clinical disability.The journal of headache and pain · 2025Article
- Article
- Plasma levels of glial fibrillary acidic protein and neurofilament light chain in patients with chronic migraine: a multicenter case-control study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Chronic Stress and Headaches: The Role of the HPA Axis and Autonomic Nervous System.Biomedicines · 2025Review
- Uncovering longitudinal changes in the brain functional connectome along the migraine cycle: a multilevel clinical connectome fingerprinting framework.The journal of headache and pain · 2025Article
- High-risk area for migraine attacks - a new concept in migraine pathophysiology.Frontiers in neurology · 2025Article
- A three-classification model for identifying migraine with right-to-left shunt using lateralization of functional connectivity and brain network topology: a resting-state fMRI study.Frontiers in neuroscience · 2024Article
- Serum neurofilament light chain levels in migraine patients: a monocentric case-control study in China.The journal of headache and pain · 2023Article
- Predicting Sumatriptan Responsiveness Based on Structural Connectivity in Patients Newly Diagnosed With Migraine.Journal of clinical neurology (Seoul, Korea) · 2023Article
- Migraine: from pathophysiology to treatment.Journal of neurology · 2023Review
- Impairments to the multisensory integration brain regions during migraine chronification: correlation with the vestibular dysfunction.Frontiers in molecular neuroscience · 2023Article
- Structural MRI in Migraine: A Review of Migraine Vascular and Structural Changes in Brain Parenchyma.Journal of central nervous system disease · 2023Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To quantitatively summarize the specific changes in brain structure and function in migraine patients. Methods: A literature screening of migraine was conducted from inception to Sept 1, 2022, in PubMed, Web of Science, Cochrane Library, and Medline databases using the keyword combination of "migraine and MRI." Activation likelihood estimation (ALE) was performed to assess the differentiation of functional connectivity (FC), regional homogeneity (ReHo), and gray matter volume (GMV) of migraine patients. Results: Eleven voxel-based morphometry (VBM) studies and 25 resting-state fMRI (rs-fMRI) studies (16 FC and 9 ReHo studies) were included in this study. ALE analysis revealed the ReHo increase in the brainstem and left thalamus, with no decreased area. Neither increased nor decreased regions were detected in FC and GMV of migraine patients. Conclusions: The left thalamus and brainstem were the significantly activated regions of migraine. It is a meaningful insights into the pathophysiology of migraine. The consistent alterated brain areas of morphometrical and functional in migraine patients were far from reached based on current studies.
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Registered trials
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