Evidence map›Paper›PMID 36419071›Full record

Trial reportWorld journal of emergency surgery : WJES2022

Outpatient management of acute uncomplicated appendicitis after laparoscopic appendectomy: a randomized controlled trial.

Jordi Elvira López, Ricard Sales Mallafré, Erlinda Padilla Zegarra, Luis Carrillo Luna, Joan Ferreres Serafini, Roisin Tully, Robert Memba Ikuga, Rosa Jorba Martin

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in World journal of emergency surgery : WJES, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05401188 nacompletednot on this map

Randomized Clinical Trial to Test the Efficacy and Safety of Outpatient Clinical Management of Urgent Laparoscopic Appendectomy in Uncomplicated Acute Appendicitis

TypeinterventionalSponsorHJ23Ran2019 to 2022Enrolled120ConditionsAppendicitis Acute, AppendicitisArmsOutpatient, hospitalization
NCT06059365 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Randomized Clinical Trial to Test the Efficacy and Safety of Outpatient Clinical Management of Urgent Laparoscopic Appendectomy in Complicated Acute Appendicitis

TypeinterventionalSponsorHJ23Ran2023 to 2023Enrolled92ConditionsAcute Appendicitis, Appendicitis Perforated, Appendicitis SuppurativeArmsHospitalization, Outpatient
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Appendicitis.Nature reviews. Disease primers · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jordi Elvira LópezGeneral and Digestive Surgery Department, University Hospital of Tarragona Joan XXIII, Rovira i Virgili University, Tarragona, Spain. jelvira.hj23.ics@gencat.cat.
Ricard Sales MallafréGeneral and Digestive Surgery Department, University Hospital of Tarragona Joan XXIII, Rovira i Virgili University, Tarragona, Spain.
Erlinda Padilla ZegarraGeneral and Digestive Surgery Department, University Hospital of Tarragona Joan XXIII, Rovira i Virgili University, Tarragona, Spain.
Luis Carrillo LunaAnesthesiology Department, University Hospital of Tarragona Joan XXIII, Rovira i Virgili University, Tarragona, Spain.
Joan Ferreres SerafiniGeneral and Digestive Surgery Department, University Hospital of Tarragona Joan XXIII, Rovira i Virgili University, Tarragona, Spain.
Roisin TullyGeneral Surgery Department, St Vincent's University Hospital, Dublin, Ireland.
Robert Memba IkugaGeneral and Digestive Surgery Department, University Hospital of Tarragona Joan XXIII, Rovira i Virgili University, Tarragona, Spain.
Rosa Jorba MartinGeneral and Digestive Surgery Department, University Hospital of Tarragona Joan XXIII, Rovira i Virgili University, Tarragona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo confirm the safety and efficacy of outpatient management of laparoscopic appendectomy, with an enhanced recovery after surgery (ERAS) protocol, in adult patients with uncomplicated acute appendicitis. Outpatient laparoscopic appendectomy is feasible and secure in selected patients in observational studies. The benefits include reduced length of stay (LOS) and postoperative complications. This is the first randomized controlled trial of outpatient management following ERAS protocol.

methodsPatients admitted from the emergency department with acute appendicitis were randomized into one of two groups: standard care within the hospital (HG) or the outpatient group (OG). An ERAS protocol was followed for both groups. Patients in the HG were admitted to the surgical ward. Patients in the OG were referred to the day-surgery unit. The primary endpoint was the length of stay.

resultsNinety-seven patients were included: 49 in the OG and 48 in the HG. LOS was significantly shorter in the OG (mean 8.82 h) than in the HG (mean 43.53 h), p < 0.001. There was no difference in readmission rates (p = 0.320); we observed only one readmission in the OG. No further emergency consultations or complications were observed. The cost saving was $516.52/patient as a result of the intervention.

conclusionOutpatient management of appendectomy is safe and feasible procedure in selected patients. This approach could become the standard of care for patients with uncomplicated appendicitis, showing fewer complications, lower LOS and cost.

trial registrationRegistration: www. CLINICALTRIALS: gov (NCT05401188) Clinical Trial ID: NCT05401188.

Indexed as

AppendicitisLaparoscopyAcute DiseaseAdultAppendectomyHumansOutpatientsAcute appendicitisAppendicitisERAS protocolLaparoscopic appendectomyOutpatient managementUncomplicated acute appendicitis

Identifiers

PMID36419071
PMCPMC9685067

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.