Evidence map›Paper›PMID 36419067›Full record

ArticleRadiation oncology (London, England)2022

Introducing new plan evaluation indices for prostate dose painting IMRT plans based on apparent diffusion coefficient images.

Saman Moradi, Bijan Hashemi, Mohsen Bakhshandeh, Amin Banaei, Bahram Mofid

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiation oncology (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Saman MoradiDepartment of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, 1411713116, Iran.
Bijan HashemiDepartment of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, 1411713116, Iran. bhashemi@modares.ac.ir.ORCID https://orcid.org/0000-0002-2511-4376
Mohsen BakhshandehDepartment of Radiology Technology, Faculty of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, 1985717443, Iran.ORCID https://orcid.org/0000-0002-6546-7483
Amin BanaeiDepartment of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, 1411713116, Iran.ORCID https://orcid.org/0000-0003-3155-1262
Bahram MofidDepartment of Radiation Oncology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, 1985717443, Iran.ORCID https://orcid.org/0000-0003-2151-3510
Tarbiat Modares University · IRShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDose painting planning would be more complicated due to different levels of prescribed doses and more complex evaluation with conventional plan quality indices considering uniform dose prescription. Therefore, we tried to introduce new indices for evaluating the dose distribution conformity and homogeneity of treatment volumes based on the tumoral cell density and relative volumes of each lesion in prostate IMRT.

methodsCT and MRI scans of 20 male patients having local prostate cancer were used for IMRT DP planning. Apparent diffusion coefficient (ADC) images were imported to a MATLAB program to identify lesion regions based on ADC values automatically. Regions with ADC values lower than 750 mm

resultsIOE (H) and IOE (C) with considering cellular density had significantly lower values compared to conventional indices and IOEs without considering cellular density. (P < 0.05). TCP values had a stronger relationship with IOE(H) considering cell density (R

conclusionIOE plan evaluation indices proposed in this study can be used for evaluating prostate IMRT dose painting plans. We suggested to consider cell densities in the IOE(H) calculation formula and it's appropriate to calculate IOE(C) without considering cell density values.

Indexed as

ProstateRadiotherapy, Intensity-ModulatedDiffusion Magnetic Resonance ImagingHumansMaleRadiotherapy DosageRadiotherapy Planning, Computer-AssistedAlgorithmic approachAnatomical parametersIntensity-modulated radiotherapyProstate cancerRadiobiology

Identifiers

PMID36419067
PMCPMC9685857
OpenAlexW4309923824

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.