Evidence map›Paper›PMID 36418971›Full record

ArticleBMC infectious diseases2022

Challenges in managing a multifactorial eosinophilic pneumonia: daptomycin vs strongyloidiasis case report.

Lynda G J Eckhardt, Jordan L Kelley, Dorothy Maes

Abstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lynda G J EckhardtDepartment of Pharmacy Services, University of Kentucky HealthCare Good Samaritan Hospital, 310 South Limestone, B003, Lexington, KY, 40536, USA. lynda.eckhardt@uky.edu.ORCID http://orcid.org/0000-0002-2581-2828
Jordan L KelleyDepartment of Pharmacy Services, University of Kentucky HealthCare Good Samaritan Hospital, 310 South Limestone, B003, Lexington, KY, 40536, USA.
Dorothy MaesDepartment of Pulmonary, Critical Care and Sleep Medicine, University of Kentucky Medical Center, Kentucky Clinic, Room K504, 740 South Limestone Street, Lexington, KY, 40536, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEosinophilia is defined as a blood eosinophil count > 500/mcL with etiology usually an allergic reaction or parasitic infection which can lead to serious organ damage. CASE PRESENTATION: A patient being treated for hardware infection develops eosinophilia while on daptomycin in the setting of a positive strongyloides antibody. The patient was on chronic steroids prior to admission for epitheliopathy which complicated care. The daptomycin was discontinued, ivermectin initiated to treat strongyloidiasis, and high dose steroids initiated simultaneously. Eosinophilia resolved and patient discharged home after two months in the hospital.

conclusionMultifactorial eosinophilia poses question of steroid harm in the setting of parasitic infection. Patient was treated for both strongyloides and daptomycin induced eosinophilia with improvement and discharge from the hospital.

Indexed as

DaptomycinPulmonary EosinophiliaStrongyloidiasisAnimalsEosinophilsHumansStrongyloidesDaptomycinCorticosteroidsDaptomycinEosinophiliaPulmonaryStrongyloides

Identifiers

PMID36418971
PMCPMC9682830

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.