Evidence map›Paper›PMID 36418906›Full record

Observational studyScientific reports2022

The prevalence of cardiac complications and their impact on outcomes in patients with non-traumatic subarachnoid hemorrhage.

Maarit Lång, Stephan M Jakob, Riikka Takala, Magnus N Lyngbakken, Anu Turpeinen, Torbjørn Omland, Tobias M Merz, Jan Wiegand, Juha Grönlund, Melissa Rahi and 4 more

Open access · goldAbstract readObservational StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 4 countries.

Maarit LångDepartment of Intensive Care Medicine, Kuopio University Hospital, University of Eastern Finland, PO BOX 100, 70029 KYS, Kuopio, Finland. maarit.lang@kuh.fi.
Stephan M JakobDepartment of Intensive Care Medicine, University Hospital of Bern, University of Bern, Bern, Switzerland.
Riikka TakalaPerioperative Services, Intensive Care Medicine and Pain Management, Turku University Hospital, Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, University of Turku, Turku, Finland.
Magnus N LyngbakkenDivision of Medicine, Department of Cardiology, Akershus University Hospital, Lørenskog, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Anu TurpeinenDepartment of Cardiology, Kuopio University Hospital, University of Eastern Finad, Kuopio, Finland.
Torbjørn OmlandDivision of Medicine, Department of Cardiology, Akershus University Hospital, Lørenskog, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Tobias M MerzDepartment of Intensive Care Medicine, University Hospital of Bern, University of Bern, Bern, Switzerland.
Jan WiegandDepartment of Intensive Care Medicine, University Hospital of Bern, University of Bern, Bern, Switzerland.
Juha GrönlundPerioperative Services, Intensive Care Medicine and Pain Management, Turku University Hospital, Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, University of Turku, Turku, Finland.
Melissa RahiNeurocenter, Department of Neurosurgery, Turku University Hospital, University of Turku, Turku, Finland.
Mika ValtonenPerioperative Services, Intensive Care Medicine and Pain Management, Turku University Hospital, Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, University of Turku, Turku, Finland.
Timo KoivistoDepartment of Neurosurgery, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland.
Helge RøsjøDivision for Research and Innovation, Akershus University Hospital, Lørenskog, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Stepani BendelDepartment of Intensive Care Medicine, Kuopio University Hospital, University of Eastern Finland, PO BOX 100, 70029 KYS, Kuopio, Finland.
University of Bern · CHUniversity of Eastern Finland · FIUniversity of Turku · FIAkershus University Hospital · NOKuopio University Hospital · FITurku University Hospital · FIUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subarachnoid hemorrhage (SAH) is a serious condition, and a myocardial injury or dysfunction could contribute to the outcome. We assessed the prevalence and prognostic impact of cardiac involvement in a cohort with SAH. This is a prospective observational multicenter study. We included 192 patients treated for non-traumatic subarachnoid hemorrhage. We performed ECG recordings, echocardiographic examinations, and blood sampling within 24 h of admission and on days 3 and 7 and at 90 days. The primary endpoint was the evidence of cardiac involvement at 90 days, and the secondary endpoint was to examine the prevalence of a myocardial injury or dysfunction. The median age was 54.5 (interquartile range [IQR] 48.0-64.0) years, 44.3% were male and the median World Federation of Neurological Surgeons (WFNS) score was 2 (IQR 1-4). At day 90, 22/125 patients (17.6%) had left ventricular ejection fractions ≤ 50%, and 2/121 patients (1.7%) had evidence of a diastolic dysfunction as defined by mitral peak E-wave velocity by peak e' velocity (E/e') > 14. There was no prognostic impact from echocardiographic evidence of cardiac complications on neurological outcomes. The overall prevalence of cardiac dysfunction was modest. We found no demographic or SAH-related factors associated with 90 days cardiac dysfunction.

Indexed as

CardiomyopathiesSubarachnoid HemorrhageEchocardiographyFemaleHumansMaleMiddle AgedPrevalenceStroke Volume

Identifiers

PMID36418906
PMCPMC9684538
OpenAlexW4309747819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.