Evidence map›Paper›PMID 36418803›Full record

ArticleCancer causes & control : CCC2023

Risk factors for endometrial cancer in Black women.

Todd R Sponholtz, Julie R Palmer, Lynn Rosenberg, Chu Chen, Yu Chen, Megan A Clarke, Tess Clendenen, Mengmeng Du, Lisa Johnson, Linda M Liao and 11 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer causes & control : CCC, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Pilot Study of Daily Exemestane in Women with Endometrial Intraepithelial Neoplasia or Low-Grade Endometrial Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Trial
  2. Article
  3. Article
  4. Understanding risk factors for endometrial cancer in young women.Journal of the National Cancer Institute · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Hypertension and Risk of Endometrial Cancer: A Pooled Analysis in the Epidemiology of Endometrial Cancer Consortium (E2C2).Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  9. Article
  10. Racioethnic Disparities in Endometrial Cancer Outcomes.Diagnostics (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 10 institutions in 1 country.

Todd R SponholtzSection of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA, USA. spnhltz@bu.edu.ORCID http://orcid.org/0000-0003-4647-5354
Julie R PalmerSlone Epidemiology Center at, Boston University, Boston, MA, USA.
Lynn RosenbergSlone Epidemiology Center at, Boston University, Boston, MA, USA.
Chu ChenFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Yu ChenDivision of Epidemiology, Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA.
Megan A ClarkeDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Tess ClendenenDivision of Epidemiology, Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA.
Mengmeng DuMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Lisa JohnsonFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Linda M LiaoDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Kara A MichelsDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Kelli O'ConnellMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Sara H OlsonMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Stacey PetruzellaMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Timothy R RebbeckDivision of Population Science, Dana-Farber Cancer Institute, Boston, MA, USA.
Veronica Wendy SetiawanKeck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Britton TrabertDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Noel S WeissUniversity of Washington, Seattle, WA, USA.
Nicholas WentzensenDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Lynne WilkensUniversity of Hawaii Cancer Center, Honolulu, HI, USA.
Lauren A WiseDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
Boston University · USMemorial Sloan Kettering Cancer Center · USNational Cancer Institute · USFred Hutch Cancer Center · USNew York University · USHarvard University · USUniversity of Hawaiʻi at Mānoa · USUniversity of Southern California · USUniversity of Utah · USUniversity of Washington · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI GERTRAUD MASKARINEC · 1996 to 2026
$56.2M
Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
RESEARCH IN ENVIRONMENTAL HEALTH SCIENCES (CENTER GRANT)P30ES000260 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ZELIKOFF, JUDITH TERRY · 1985 to 2020
$26.1M
A Follow-up Study for Causes of Cancer in Black WomenU01CA164974 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Kimberly A. Bertrand, Yvette C Cozier · 2017 to 2026
$24.0M
GENETIC SUSCEPTIBILITY TO CANCER IN MULTIETHNIC COHORTSR01CA063464 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HENDERSON, BRIAN E · 2001 to 2005
$23.2M
Multiethnic Cohort Study of Diet and CancerR37CA054281 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI KOLONEL, LAURENCE N. · 2003 to 2012
$23.2M
FOLLOW-UP STUDY FOR CAUSES OF ILLNESS IN BLACK WOMENR01CA058420 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ROSENBERG, LYNN · 1999 to 2013
$20.7M
A Follow-up Study for Causes of Cancer in Black WomenUM1CA164974 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ROSENBERG, LYNN · 2012 to 2017
$13.7M
Multidisciplinary Training in Cardiovascular ResearchT32HL007224 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HAMBURG, NAOMI MIRIAM, WAINFORD, RICHARD DAVID · 1985 to 2020
$12.3M
Understanding Ethnic Differences in Cancer: The Multiethnic Cohort StudyUM1CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HENDERSON, BRIAN E, LE MARCHAND, LOIC · 2012 to 2014
$11.3M
NCI NIH HHS K05 CA092002NCI NIH HHS P01 CA077596NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA016087NCI NIH HHS P30 CA071789NCI NIH HHS R01 CA054281NCI NIH HHS R01 CA058420NCI NIH HHS R01 CA063464NCI NIH HHS R01 CA083918NCI NIH HHS R01 CA087538NCI NIH HHS R01 CA098661NCI NIH HHS R01 CA105212NCI NIH HHS R03 CA080636NCI NIH HHS R03 CA169888NCI NIH HHS R37 CA054281NCI NIH HHS U01 CA063464NCI NIH HHS U01 CA164973NCI NIH HHS U01 CA164974NCI NIH HHS U01 CA182934NCI NIH HHS U01 CA250476NCI NIH HHS UM1 CA164973NCI NIH HHS UM1 CA164974NHLBI NIH HHS T32 HL007224NHLBI NIH HHS T32 HL125232NICHD NIH HHS N01 HD023166NIEHS NIH HHS ES000260NIEHS NIH HHS P30 ES000260NIH HHS R01 CA75977
6 · The paper itself

Abstract

purposeThe incidence of endometrial cancer (EC) has been increasing faster among Black women than among other racial/ethnic groups in the United States. Although the mortality rate is nearly twice as high among Black than White women, there is a paucity of literature on risk factors for EC among Black women, particularly regarding menopausal hormone use and severe obesity.

methodsWe pooled questionnaire data on 811 EC cases and 3,124 controls from eight studies with data on self-identified Black women (4 case-control and 4 cohort studies). We analyzed cohort studies as nested case-control studies with up to 4 controls selected per case. We used logistic regression to estimate multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs).

resultsWe observed a positive association between BMI and EC incidence (P

conclusionsOur results suggest that the associations of established risk factors with EC are similar between Black and White women. Other explanations, such as differences in the prevalence of known risk factors or previously unidentified risk factors likely underlie the recent increases in EC incidence among Black women.

Indexed as

Black or African AmericanEndometrial NeoplasmsCohort StudiesEstrogen Replacement TherapyEstrogensFemaleHumansObesityRisk FactorsSurveys and QuestionnairesUnited StatesEstrogensBlack womenEndometrial cancerExogenous hormonesObesityReproductive history

Identifiers

PMID36418803
PMCPMC10106410
OpenAlexW4309927917

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.