Evidence map›Paper›PMID 36418644›Full record

ArticleSocial psychiatry and psychiatric epidemiology2023

Association of childhood threat and deprivation with depressive symptoms and the moderating role of current economic status among middle-aged and older adults in China.

Li Lin, Bing Cao, Weiqing Chen, Jinghua Li, Yuying Zhang, Vivian Yawei Guo

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Article in Social psychiatry and psychiatric epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

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9citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Li LinDepartment of Epidemiology, School of Public Health, Sun Yat-Sen University, 74 Zhongshan Second Road, Guangzhou, 510080, Guangdong, China.
Bing CaoDepartment of Neurosurgery, Wu Tsai Neuroscience Institute, Stanford University School of Medicine, Stanford, CA, USA. bingcao@stanford.edu.
Weiqing ChenDepartment of Epidemiology, School of Public Health, Sun Yat-Sen University, 74 Zhongshan Second Road, Guangzhou, 510080, Guangdong, China.
Jinghua LiDepartment of Biostatistics, School of Public Health, Sun Yat-Sen University, Guangzhou, China.
Yuying ZhangDepartment of Child Healthcare, Shenzhen Longhua Maternity and Child Healthcare Hospital, Shenzhen, China.
Vivian Yawei GuoDepartment of Epidemiology, School of Public Health, Sun Yat-Sen University, 74 Zhongshan Second Road, Guangzhou, 510080, Guangdong, China. guoyw23@mail.sysu.edu.cn.

Funding

The Fundamental Research Funds for the Central Universities, Sun Yat-sen University 22qntd4201The start-up fund from the Sun Yat-sen University 51000-18841211
6 · The paper itself

Abstract

purposeTo investigate the independent impact of threat-related and deprivation-related adverse childhood experiences (ACEs) on depressive symptoms among middle-aged and older adults, and to evaluate the moderating role of current economic status in these associations.

methodsThis cross-sectional study included 11,048 participants aged ≥ 45 years from the China Health and Retirement Longitudinal Study. We captured five threat-related ACEs and five deprivation-related ACEs by questionnaires. Depressive symptoms were assessed using the 10-item Centre for Epidemiological Studies Depression Scale. Current economic status was reflected by annual per capita household consumption expenditure. We performed logistic regression analyses to evaluate the independent association of childhood threat and deprivation with depressive symptoms, and conducted stratified analyses and tests for interaction to explore the moderation effect of current economic status in such associations.

resultsCompared with the nonexposed group, the experience of both childhood threat and deprivation were independently associated with greater risks of depressive symptoms later in life (odds ratio [OR] 1.75, 95% CI 1.49-2.05 for ≥ 2 threat-related ACEs; OR 2.02, 95% CI 1.67-2.43 for ≥ 2 deprivation-related ACEs). High current economic status significantly ameliorated the impact of childhood deprivation, but not threat, on depressive symptoms (P value for interaction 0.038).

conclusionsBoth threat-related and deprivation-related ACEs were associated with the risk of depressive symptoms among middle-aged and older adults, while current economic status was a significant moderator in such risks only for childhood deprivation. The findings implied that prioritising targeted interventions for individuals with ACEs, especially for childhood deprivation victims who were economically disadvantaged in adulthood, may help mitigate depressive symptoms in later life.

Indexed as

Adverse Childhood ExperiencesDepressionEconomic StatusMediation AnalysisAgedChildChinaCross-Sectional StudiesFemaleHumansLogistic ModelsLongitudinal StudiesMaleMiddle AgedOdds RatioRetirementAdverse childhood experiencesDepressive symptomsDeprivationEconomic statusOlder adultsThreat

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.