Evidence map›Paper›PMID 36418601›Full record

SynthesisArchives of dermatological research2023

Use of propolis for skin wound healing: systematic review and meta-analysis.

Julia Carnelós Machado Velho, Thais Amaral França, Maria José Malagutti-Ferreira, Edilson Rodrigues Albuquerque, Francislaine Aparecida Dos Reis Lívero, Murilo Racy Soares, Ademilson Espencer Egea Soares, João Tadeu Ribeiro-Paes

Open access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Archives of dermatological research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Julia Carnelós Machado VelhoDepartment of Biotechnology, São Paulo State University (UNESP), Assis, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-1928-5299
Thais Amaral FrançaDepartment of Biotechnology, São Paulo State University (UNESP), Assis, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-8252-0699
Maria José Malagutti-FerreiraDepartment of Biotechnology, São Paulo State University (UNESP), Assis, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-5174-5502
Edilson Rodrigues AlbuquerquePreclinical Research Laboratory of Natural Products, Universidade Paranaense (UNIPAR), Umuarama, Paraná, Brazil.ORCID http://orcid.org/0000-0001-5773-9912
Francislaine Aparecida Dos Reis LíveroPreclinical Research Laboratory of Natural Products, Universidade Paranaense (UNIPAR), Umuarama, Paraná, Brazil.ORCID http://orcid.org/0000-0001-6533-0850
Murilo Racy SoaresDepartment of Obstetrics and Gynecology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-4190-495X
Ademilson Espencer Egea SoaresDepartment of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-0180-0635
João Tadeu Ribeiro-PaesDepartment of Biotechnology, São Paulo State University (UNESP), Assis, São Paulo, Brazil. ribeiro.paes@unesp.br.ORCID http://orcid.org/0000-0002-7645-5891
Universidade Estadual Paulista (Unesp) · BRUniversidade de São Paulo · BRUniversidade Paranaense · BRFundação de Apoio à Universidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Propolis is a natural resin that is produced by bees. It has anti-inflammatory and antibiotic properties, promotes reepithelization, and stimulates skin regeneration. Propolis has great potential for the development of new therapeutic approaches to treat skin ulcers. The present study performed a systematic review and meta-analysis of published studies of the use of propolis for the regeneration of cutaneous wounds and its efficacy as a therapeutic agent. Data were collected from articles in the PubMed, SCOPUS, and Web of Science databases that were published since 1900 by searching the terms "propolis" AND "wound healing." This search yielded 633 articles, of which 43 were included in this systematic review and meta-analysis. The results showed that interest in the therapeutic efficacy of propolis has increased over the years. The studies reported that the propolis was effective for the treatment of skin ulcers by promoting a higher percentage of healing than classically employed interventions. The mode of propolis application has also evolved. An increasing number of studies combined it with other substances and materials to achieve additive or synergistic effects on the skin regeneration process. Propolis appears to be an effective therapeutic alternative for the treatment of skin ulcers.

Indexed as

PropolisSkin UlcerAnti-Bacterial AgentsHumansSkinWound HealingAnti-Bacterial AgentsPropolisAlternative therapyDressingsNatural productsSkin woundsWound regeneration

Identifiers

PMID36418601
OpenAlexW4309821876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.