ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2023
The relationship between memory and quality of life is mediated by trait anxiety in patients with temporal lobe epilepsy.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 4 of them syntheses that pooled it.
What it found
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Who cites it
7 citing papers in PubMed, 4 syntheses or guidelines pooled it, 11 citations in OpenAlex.
- Examining the Effectiveness of Neuropsychological Interventions on Cognition in Patients with Epilepsy: A Systematic Review and Meta-Analysis.Neuropsychology review · 2026Pooled it
- Sex and gender differences in memory in epilepsy: a systematic review and meta-analysis.Biology of sex differences · 2025Pooled it
- Determinants of health-related quality of life of patients with focal epilepsy: A systematic literature review.Epileptic disorders : international epilepsy journal with videotape · 2025Pooled it
- Systematic literature review of the humanistic and economic burden of focal epilepsy and primary generalized tonic-clonic seizures in adults.Epilepsia open · 2024Pooled it
- Evidence for the Induction of Anxiolytic-Like Behavior and Memory Preservation by (+)-Dihydrocarvone Through Studies in Adult Zebrafish and In Sílico.Chemistry & biodiversity · 2026Article
- Affective and Cognitive Vulnerability Under Chronic Stress: Insights From Patients With Left Temporal Lobe Epilepsy and Caregivers.Actas espanolas de psiquiatria · 2026Article
- Stress phenotypes in epilepsy: impact on cognitive functioning and quality of life.Frontiers in psychology · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
purposeMemory deficits are very frequent in patients with drug-resistant epilepsy, but they predict a small proportion of variance of their quality of life (QOL) in previous studies, possibly due to the lack of consideration of mediating factors of this relationship. This study aimed to examine whether trait anxiety mediates the relationship between memory and QOL in this population, controlling the influence of demographic and seizure-related factors.
methodsIn this cross-sectional study, 119 adults with drug-resistant temporal lobe epilepsy (TLE) underwent a neuropsychological evaluation, in which memory, anxiety, and QOL were assessed.
resultsIn the total sample, better delayed memory had an effect on better QOL indirectly through lower trait anxiety (B = 0.13, SE = 0.06, p = 0.04, ab
conclusionThese findings suggest that trait anxiety is an important factor in understanding the relationship between memory and QOL in patients with TLE, considering the influence of demographic and seizure-related variables, and may have relevant implications for decision-making in this population.
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