Evidence map›Paper›PMID 36418516›Full record

ArticleScientific reports2022

Span of regularization for solution of inverse problems with application to magnetic resonance relaxometry of the brain.

Chuan Bi, M Yvonne Ou, Mustapha Bouhrara, Richard G Spencer

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chuan BiDepartment of Psychiatry, University of Maryland, Baltimore, Baltimore, MD, 21201, USA. chuan.bi@som.umaryland.edu.
M Yvonne OuDepartment of Mathematical Sciences, University of Delaware, Newark, DE, 19716, USA.
Mustapha BouhraraNational Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
Richard G SpencerNational Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a new regularization method for the solution of the Fredholm integral equation (FIE) of the first kind, in which we incorporate solutions corresponding to a range of Tikhonov regularizers into the end result. This method identifies solutions within a much larger function space, spanned by this set of regularized solutions, than is available to conventional regularization methods. An additional key development is the use of dictionary functions derived from noise-corrupted inversion of the discretized FIE. In effect, we combine the stability of solutions with greater degrees of regularization with the resolution of those that are less regularized. The span of regularizations (SpanReg) method may be widely applicable throughout the field of inverse problems.

Indexed as

AlgorithmsMagnetic Resonance ImagingBrainMagnetic Resonance Spectroscopy

Identifiers

PMID36418516
PMCPMC9684479

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.