Evidence map›Paper›PMID 36418183›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Deletion of

Alison Heffer, Felicia A Gilels, Amy E Kiernan

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  4. bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alison HefferFlaum Eye Institute, Department of Ophthalmology, University of Rochester Medical Center, Rochester, New York 14642.
Felicia A GilelsFlaum Eye Institute, Department of Ophthalmology, University of Rochester Medical Center, Rochester, New York 14642.
Amy E KiernanFlaum Eye Institute, Department of Ophthalmology, University of Rochester Medical Center, Rochester, New York 14642 amy_kiernan@urmc.rochester.edu.
University of Rochester Medical Center · US

Funding

Sensory Organ Formation in the Inner EarR01DC009250 · NIDCD · UNIVERSITY OF ROCHESTER · PI KIERNAN, AMY · 2009 to 2019
$3.8M
Notch Signaling during Organ of Corti Maturation and MaintenanceR01DC017767 · NIDCD · UNIVERSITY OF ROCHESTER · PI KIERNAN, AMY · 2020 to 2024
$1.9M
The role of Notch signaling in the maintenance and function of cochlear sensory cellsF31DC018198 · NIDCD · UNIVERSITY OF ROCHESTER · PI GILELS, FELICIA AILEEN · 2019 to 2021
$137k
NIDCD NIH HHS F31 DC018198NIDCD NIH HHS R01 DC009250NIDCD NIH HHS R01 DC017767
6 · The paper itself

Abstract

The sensory region of the mammalian hearing organ contains two main cell types-hair cells and supporting cells. During development, Notch signaling plays an important role in whether a cell becomes either a hair cell or supporting cell by mediating lateral inhibition. However, once the cell fate decisions have been determined, little is understood about the role Notch plays in cochlear maturation. Here, we report that deletion of

Indexed as

CochleaDeafnessAnimalsCell DeathCell DifferentiationFemaleHair Cells, Auditory, OuterMaleMammalsMiceReceptor, Notch1Notch1 protein, mouseReceptor, Notch1cell deathcochleadeafnesshair cellsNotchsupporting cells

Identifiers

PMID36418183
PMCPMC9838715
OpenAlexW4309866804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.