ArticleeNeuro
Interictal Gamma Event Connectivity Differentiates the Seizure Network and Outcome in Patients after Temporal Lobe Epilepsy Surgery.
Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 17 citations in OpenAlex.
- Stronger pre-surgical functional connectivity networks are associated with improved surgical outcome in temporal lobe epilepsy.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Identifying the epileptic network by linking interictal functional and structural connectivity.Scientific reports · 2025Article
- Preictal connectivity dynamics: Exploring inflow and outflow in iEEG networks.Frontiers in network physiology · 2025Article
- Independent component analysis of resting-state fMRI identifies regions associated with seizure freedom after laser interstitial thermal therapy for temporal lobe epilepsy.Frontiers in neurology · 2025Article
- Influence of mindfulness meditation on intracranial EEG parameters in epileptic and non-epileptic brain areas.Epilepsy & behavior : E&B · 2024Article
- Stereotactic Electroencephalogram Recordings in Temporal Lobectomy Patients Demonstrates the Predictive Value of Interictal Cross-Frequency Correlations: A Retrospective Study.Brain sciences · 2024Article
- The Surgical Method of Craniectomy Differentially Affects Acute Seizures, Brain Deformation, and Behavior in a Traumatic Brain Injury Animal Model.Neurotrauma reports · 2024Article
- Therapeutic approaches targeting seizure networks.Frontiers in network physiology · 2024Review
- High-rate leading spikes in propagating spike sequences predict seizure outcome in surgical patients with temporal lobe epilepsy.Brain communications · 2023Article
- Physiological and pathological neuronal connectivity in the living human brain based on intracranial EEG signals: the current state of research.Frontiers in network physiology · 2023Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies of interictal EEG functional connectivity in the epileptic brain seek to identify abnormal interactions between brain regions involved in generating seizures, which clinically often is defined by the seizure onset zone (SOZ). However, there is evidence for abnormal connectivity outside the SOZ (NSOZ), and removal of the SOZ does not always result in seizure control, suggesting, in some cases, that the extent of abnormal connectivity indicates a larger seizure network than the SOZ. To better understand the potential differences in interictal functional connectivity in relation to the seizure network and outcome, we computed event connectivity in the theta (4-8 Hz, ThEC), low-gamma (30-55 Hz, LGEC), and high-gamma (65-95 Hz, HGEC) bands from interictal depth EEG recorded in surgical patients with medication-resistant seizures suspected to begin in the temporal lobe. Analysis finds stronger LGEC and HGEC in SOZ than NSOZ of seizure-free (SF) patients (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.