Evidence map›Paper›PMID 36418127›Full record

Observational studyBMJ open2022

Investigating transmission of SARS-CoV-2 using novel face mask sampling: a protocol for an observational prospective study of index cases and their contacts in a congregate setting.

Thomas Jaenisch, Molly M Lamb, Emily N Gallichotte, Brian Adams, Charles Henry, Jeannine Riess, Joni Triantis van Sickle, Kellie L Hawkins, Brian T Montague, Cody Coburn and 19 more

Registry-linked trialOpen access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05145803 (Asymptomatic and Pre-symptomatic Transmission of SARS-CoV-2 in a Community Congregant Setting), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05145803 unknown statusnot on this map

Asymptomatic and Pre-symptomatic Transmission of SARS-CoV-2 in a Community Congregant Setting: a Study to Understand How Infection Control Practices Can Mitigate Exposure Risks

TypeobservationalSponsorColorado School of Public HealthRan2021 to 2022Enrolled3,300ConditionsCOVID-19, SARS-CoV2 InfectionArmsPolyvinylalcohol strip [diagnostic]
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 9 institutions in 3 countries.

Thomas JaenischCenter for Global Health and Department of Epidemiology, Colorado School of Public Health, Aurora, Colorado, USA thomas.jaenisch@cuanschutz.edu.ORCID 0000-0002-9464-571X
Molly M LambCenter for Global Health and Department of Epidemiology, Colorado School of Public Health, Aurora, Colorado, USA.
Emily N GallichotteDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Brian AdamsCenter for Global Health, Colorado School of Public Health, Aurora, Colorado, USA.
Charles HenryDepartment of Chemical and Biological Engineering, Colorado State University, Fort Collins, Colorado, USA.
Jeannine RiessOffice of Environmental Health Services, Colorado State University, Fort Collins, Colorado, USA.
Joni Triantis van SickleOffice of Environmental Health Services, Colorado State University, Fort Collins, Colorado, USA.
Kellie L HawkinsPublic Health Institute, Denver Health, Denver, Colorado, USA.
Brian T MontagueOccupational Health and Division of Infectious Diseases, University of Colorado School of Medicine, Denver, Colorado, USA.
Cody CoburnOccupational Health and Division of Infectious Diseases, University of Colorado School of Medicine, Denver, Colorado, USA.
Leisha Conners BauerHealth Promotion and Collegiate Recovery Center, University of Colorado Boulder, Boulder, Colorado, USA.
Jennifer KovarikHealth Promotion and Collegiate Recovery Center, University of Colorado Boulder, Boulder, Colorado, USA.
Mark T HernandezCivil, Environmental and Architectural Engineering, University of Colorado Boulder, Boulder, Colorado, USA.
Amy BronsonOffice of the Vice President, Colorado Mesa University, Grand Junction, Colorado, USA.
Lucy GrahamDepartment of Health Sciences, Colorado Mesa University, Grand Junction, Colorado, USA.
Stephanie JamesDepartment of Pharmaceutical Sciences, Regis University, Denver, Colorado, USA.
Stephanie HanenbergWellness Center, University of Colorado Colorado Springs, Colorado Springs, Colorado, USA.
James KovacsDepartment of Chemistry and Biology, University of Colorado Colorado Springs, Colorado Springs, Colorado, USA.
John S SpencerDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Mark ZabelDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Philip D FoxDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Olivia PlussCenter for Global Health, Colorado School of Public Health, Aurora, Colorado, USA.
William WindsorCenter for Global Health, Colorado School of Public Health, Aurora, Colorado, USA.
Geoffrey WinstanleyCenter for Global Health, Colorado School of Public Health, Aurora, Colorado, USA.
Daniel OlsonCenter for Global Health, Colorado School of Public Health, Aurora, Colorado, USA.
Michael BarerDepartment of Infectious Diseases, University of Leicester, Leicester, Leicestershire, UK.
Stephen BermanCenter for Global Health, Colorado School of Public Health, Aurora, Colorado, USA.
Gregory EbelDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA.
May ChuCenter for Global Health, Colorado School of Public Health, Aurora, Colorado, USA.
Colorado School of Public Health · USColorado State University · USUniversity of Colorado Boulder · USColorado Mesa University · USUniversity of Colorado Colorado Springs · USUniversity of Colorado Denver · USDenver Health Medical Center · USRegis University · USUniversity of Leicester · GB

Funding

Medical Research Council MC_PC_16051
6 · The paper itself

Abstract

introductionThis study aims to measure how transmission of SARS-CoV-2 occurs in communities and to identify conditions that lend to increased transmission focusing on congregate situations. We will measure SARS-CoV-2 in exhaled breath of asymptomatic and symptomatic persons using face mask sampling-a non-invasive method for SARS-CoV-2 detection in exhaled air. We aim to detect transmission clusters and identify risk factors for SARS-CoV-2 transmission in presymptomatic, asymptomatic and symptomatic individuals. METHODS AND ANALYSIS: In this observational prospective study with daily follow-up, index cases and their respective contacts are identified at each participating institution. Contact definitions are based on Centers for Disease Control and Prevention and local health department guidelines. Participants will wear masks with polyvinyl alcohol test strips adhered to the inside for 2 hours daily. The strips are applied to all masks used over at least 7 days. In addition, self-administered nasal swabs and (optional) finger prick blood samples are performed by participants. Samples are tested by standard PCR protocols and by novel antigen tests. ETHICS AND DISSEMINATION: This study was approved by the Colorado Multiple Institutional Review Board and the WHO Ethics Review Committee. From the data generated, we will analyse transmission clusters and risk factors for transmission of SARS-CoV-2 in congregate settings. The kinetics of asymptomatic transmission and the evaluation of non-invasive tools for detection of transmissibility are of crucial importance for the development of more targeted control interventions-and ultimately to assist with keeping congregate settings open that are essential for our social fabric. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov (#NCT05145803).

Indexed as

COVID-19MasksHumansObservational Studies as TopicPersonal Protective EquipmentProspective StudiesSARS-CoV-2COVID-19Diagnostic microbiologyVirology

Identifiers

PMID36418127
PMCPMC9684274
OpenAlexW4309821998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.