Evidence map›Paper›PMID 36418095›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Fulminant Myocarditis and Acute Appendicitis after COVID-19 Vaccination.

Hiroaki Kawano, Nobu Yamamoto, Hirokazu Kurohama, Shinji Okano, Masaya Kurobe, Tomohiro Honda, Ryohei Akashi, Tsuyoshi Yonekura, Satoshi Ikeda, Koichi Izumikawa and 1 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Acute abdomen following COVID-19 vaccination: a systematic review.Clinical and experimental vaccine research · 2024
    Article
  4. SARS-CoV-2 vaccines and myocarditis.Clinical medicine (London, England) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Hiroaki KawanoDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Nobu YamamotoDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Hirokazu KurohamaDepartment of Pathology, Nagasaki University Hospital, Japan.
Shinji OkanoDepartment of Pathology, Nagasaki University Hospital, Japan.
Masaya KurobeDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Tomohiro HondaDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Ryohei AkashiDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Tsuyoshi YonekuraDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Satoshi IkedaDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Koichi IzumikawaInfection Control and Education Center, Nagasaki University Hospital, Japan.
Koji MaemuraDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Nagasaki University · JPNagasaki University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 19-year-old Japanese man was hospitalized for cardiogenic shock 28 days after receiving a second dose of the coronavirus disease 2019 (COVID-19) mRNA-1273 vaccine. He had had a high fever for three days with vomiting and abdominal pain before arriving at our hospital. The patient visited a local hospital and was diagnosed with heart failure and acute appendicitis. An endomyocardial biopsy specimen showed myocarditis. Thereafter, Impella CP left ventricular assist device implantation and venoarterial peripheral extracorporeal membranous oxygenation were initiated immediately along with inotropic support and steroid pulse therapy. Given these findings, he was finally diagnosed with multiple inflammatory syndrome and fulminant myocarditis.

Indexed as

AppendicitisCOVID-19Heart-Assist DevicesMyocarditis2019-nCoV Vaccine mRNA-1273Acute DiseaseAdultCOVID-19 VaccinesHumansMaleShock, CardiogenicTreatment OutcomeYoung Adult2019-nCoV Vaccine mRNA-1273COVID-19 Vaccinesbiopsycytokineinflammation

Identifiers

PMID36418095
PMCPMC9970817
OpenAlexW4309643771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.