Evidence map›Paper›PMID 36417948›Full record

ArticleJournal of pharmaceutical sciences2023

Characterization of Porcine Gingiva for Drug Absorption.

Apipa Wanasathop, Cheng Zhong, Patcharawan Nimmansophon, Michael Murawsky, S Kevin Li

Open access · greenAbstract read
In one paragraph

Article in Journal of pharmaceutical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Iontophoresis on Porcine and Human Gingiva.Pharmaceutical research · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Apipa WanasathopDivision of Pharmaceutical Sciences, College of Pharmacy, University of Cincinnati, Cincinnati, OH, 45267, USA.
Cheng ZhongDivision of Pharmaceutical Sciences, College of Pharmacy, University of Cincinnati, Cincinnati, OH, 45267, USA.
Patcharawan NimmansophonDivision of Pharmaceutical Sciences, College of Pharmacy, University of Cincinnati, Cincinnati, OH, 45267, USA.
Michael MurawskyDivision of Pharmaceutical Sciences, College of Pharmacy, University of Cincinnati, Cincinnati, OH, 45267, USA.
S Kevin LiDivision of Pharmaceutical Sciences, College of Pharmacy, University of Cincinnati, Cincinnati, OH, 45267, USA. Electronic address: kevin.li@uc.edu.
University of Cincinnati Medical Center · USUniversity of Cincinnati · US

Funding

Characterization of gingival drug delivery to improve local treatmentR15DE028701 · NIDCR · UNIVERSITY OF CINCINNATI · PI LI, KEVIN S. · 2019 to 2019
$481k
NIDCR NIH HHS R15 DE028701
6 · The paper itself

Abstract

Gingiva or gum is a part of the periodontium that surrounds the tooth. Its main function is to provide an effective barrier to both mechanical trauma and bacterial invasion. Gingiva is the target site for some topical drugs. The most common disease in gingiva is periodontal diseases (gum infections). Understanding the gingiva barrier properties could provide insights into approaches to effective drug delivery for the gingiva. Porcine gingiva was chosen as the model in the present membrane transport study. The permeability coefficients of gingiva were determined using a modified Franz diffusion cell with small diffusional area (0.03 cm

Indexed as

GingivaWaterAnimalsBiological TransportDiffusionOctanolsPermeabilityPharmaceutical PreparationsSwineOctanolsPharmaceutical PreparationsWaterDiffusion cellOral mucosaPermeabilityPorcine gingivaTransport

Identifiers

PMID36417948
PMCPMC10033335
OpenAlexW4309425401

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.