Evidence map›Paper›PMID 36417910›Full record

ArticleESC heart failure2023

Multisystem inflammatory syndrome and lymphohistiocytic myocarditis after Covid-19 vaccine in a middle-aged woman.

Kosuke Kobayashi, Yasuhiro Hamatani, Koki Moriyoshi, Moritake Iguchi, Nobutoyo Masunaga, Mariko Terashima, Mitsuru Abe, Nozomu Sasahashi, Masaharu Akao

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kosuke KobayashiDepartment of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Yasuhiro HamataniDepartment of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Koki MoriyoshiDepartment of Diagnostic Pathology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Moritake IguchiDepartment of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Nobutoyo MasunagaDepartment of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Mariko TerashimaDepartment of Trauma and Critical Care, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Mitsuru AbeDepartment of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Nozomu SasahashiDepartment of Trauma and Critical Care, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Masaharu AkaoDepartment of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.ORCID 0000-0002-2348-7646
Kyoto Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a 51-year-old otherwise healthy woman hospitalized for hypotension, fever, and weakness 4 days after the second-dose Covid-19 mRNA vaccine. Elevated inflammatory markers, natriuretic peptide levels and troponin levels, and slightly reduced left ventricular ejection fraction of 50% were noted. We also found the multiple organ damage, including mucocutaneous, gastrointestinal, and neurologic systems. In addition, we revealed the positive results for anti-nucleocapsid SARS-CoV-2 IgG, albeit negative for SARS-CoV-2 polymerase chain reaction testing, suggesting the prior asymptomatic Covid-19 infection. We finally diagnosed her as multisystem inflammatory syndrome after vaccination. Of note, we obtained myocardial specimen from the patients and demonstrated the lymphohistiocytic myocarditis, which is a rare form of myocarditis.

Indexed as

COVID-19COVID-19 VaccinesMyocarditisFemaleHumansMiddle AgedSARS-CoV-2Stroke VolumeVentricular Function, LeftCOVID-19 VaccinesCovid-19Multisystem inflammatory syndromeMyocarditisVaccination

Identifiers

PMID36417910
PMCPMC10053174
OpenAlexW4309859260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.