Evidence map›Paper›PMID 36417692›Full record

ArticleBiomacromolecules2022

Species-Based Differences in Mechanical Properties, Cytocompatibility, and Printability of Methacrylated Collagen Hydrogels.

Sarah M Ali, Nashaita Y Patrawalla, Nilabh S Kajave, Alan B Brown, Vipuil Kishore

Open access · greenAbstract read
In one paragraph

Article in Biomacromolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sarah M AliDepartment of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, Florida32901, United States.
Nashaita Y PatrawallaDepartment of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, Florida32901, United States.
Nilabh S KajaveDepartment of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, Florida32901, United States.
Alan B BrownDepartment of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, Florida32901, United States.
Vipuil KishoreDepartment of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, Florida32901, United States.ORCID 0000-0002-2559-1789
Florida Institute of Technology · US

Funding

3D Printed Biomimetic Bioglass-Gradient Matrices for ACL ReconstructionR15AR071102 · NIAMS · FLORIDA INSTITUTE OF TECHNOLOGY · PI KISHORE, VIPUIL · 2017 to 2023
$827k
NIAMS NIH HHS R15 AR071102
6 · The paper itself

Abstract

Collagen methacrylation is a promising approach to generate photo-cross-linkable cell-laden hydrogels with improved mechanical properties. However, the impact of species-based variations in amino acid composition and collagen isolation method on methacrylation degree (MD) and its subsequent effects on the physical properties of methacrylated collagen (CMA) hydrogels and cell response are unknown. Herein, we compared the effects of three collagen species (bovine, human, and rat), two collagen extraction methods (pepsin digestion and acid extraction), and two photoinitiators (lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) and Irgacure-2959 (I-2959)) on the physical properties of CMA hydrogels, printability and mesenchymal stem cell (MSC) response. Human collagen showed the highest MD. LAP was more cytocompatible than I-2959. The compressive modulus and cell viability of rat CMA were significantly higher (

Indexed as

HydrogelsMesenchymal Stem CellsAnimalsCattleCell SurvivalCollagenHumansRatsTissue EngineeringCollagenHydrogels

Identifiers

PMID36417692
PMCPMC11103796
OpenAlexW4309809879

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.