Evidence map›Paper›PMID 36417640›Full record

ArticleRevista da Associacao Medica Brasileira (1992)2022

Impressions of the chronic 900-MHz electromagnetic field in the prenatal period on Purkinje cells in male rat pup cerebella: is it worth mentioning?

Orhan Bas, Ilker Sengul, Ozge Fatma Mengi Bas, Hatice Hanci, Muhammet Degermenci, Demet Sengul, Emrah Altuntas, Umut Serkan Soztanaci, Osman Fikret Sonmez, José Maria Soares Junior

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Revista da Associacao Medica Brasileira (1992), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.1field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 4 countries.

Orhan BasSamsun University, Faculty of Medicine, Department of Anatomy - Samsun, Turkey.ORCID http://orcid.org/0000-0002-7449-2699
Ilker SengulGiresun University, Faculty of Medicine, Division of Endocrine Surgery - Giresun, Turkey.ORCID http://orcid.org/0000-0001-5217-0755
Ozge Fatma Mengi BasAglasun State Hospital, Department of Family Medicine - Burdur, Turkey.ORCID http://orcid.org/0000-0002-3935-3941
Hatice HanciOrdu University, Faculty of Medicine, Department of Histology and Embryology - Ordu, Turkey.ORCID http://orcid.org/0000-0002-4056-763X
Muhammet DegermenciOrdu University, Faculty of Medicine, Department of Anatomy - Ordu, Turkey.ORCID http://orcid.org/0000-0002-4751-6202
Demet SengulGiresun University, Faculty of Medicine, Department of Pathology - Giresun, Turkey.ORCID http://orcid.org/0000-0002-0416-0621
Emrah AltuntasTerme State Hospital, Department of Emergency Surgery - Samsun, Turkey.ORCID http://orcid.org/0000-0002-1180-6275
Umut Serkan SoztanaciHealth Sciences University, Faculty of Medicine, Department of Anatomy - Istanbul, Turkey.ORCID http://orcid.org/0000-0002-7100-9067
Osman Fikret SonmezHealth Sciences University, Faculty of Medicine, Department of Neurosurgery - Izmir, Turkey.ORCID http://orcid.org/0000-0003-1050-1645
José Maria Soares JuniorUniversidade Federal de São Paulo, Endocrinologia Ginecológica da Faculdade de Medicina - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0003-0774-9404
Giresun University · TROrdu University · TRSivas State Hospital · TRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRIzmir University · TRSağlık Bilimleri Üniversitesi · TRState Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to examine the changes on the Purkinje cells in the cerebella of male rat pups born to pregnant dams that were exposed to an electromagnetic field in the prenatal period.

methodsThe first stage of the study involved 12 Sprague-Dawley rats, 6 male and 6 female, weighing between 180 and 250 g. The female rats in the experimental group were exposed to a 900-MHz electromagnetic field for 1 h at the same time every day, and no procedure was performed on the control group. Following pregnancy, six male pups from each group were divided into experimental and control groups without any procedure on the pups. After 2 months, they were sacrificed and their cerebella were removed. Histopathologically, following routine processing and fixation procedures, the cerebella were embedded in the tissue blocks. The sections taken from these blocks were stained with cresyl violet. The Purkinje cells in the cerebella were then counted on sections using the optical dissector method on an image analysis system.

resultsThe estimation of number of the Purkinje cells in the groups revealed more cells in rats in the control group than in the experimental group. Histopathologically, Purkinje cells exhibited a normal morphological structure in the control group, while the cells in the experimental group showed damage.

conclusionsIt might be asserted that the exposure of mothers to an electromagnetic field in the prenatal period may affect the development of Purkinje cells in the pup cerebella.

Indexed as

Electromagnetic FieldsPurkinje CellsAnimalsFemaleMalePregnancyRatsRats, Sprague-DawleyVitaminsVitamins

Identifiers

PMID36417640
PMCPMC9683916
OpenAlexW4309535734

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.