Evidence map›Paper›PMID 36417426›Full record

SynthesisThe international journal of medical robotics + computer assisted surgery : MRCAS2023

Indocyanine green (ICG) fluorescence in robotic hepatobiliary surgery: A systematic review.

Archit V Potharazu, Antonio Gangemi

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in The international journal of medical robotics + computer assisted surgery : MRCAS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Indocyanine green (ICG) fluorescence in robotic hepatobiliary surgery: A systematic review.The international journal of medical robotics + computer assisted surgery : MRCAS · 2023
    Pooled it
  5. Article
  6. Article
  7. Article
  8. Review
  9. LaparoscopicWorld journal of hepatology · 2025
    Article
  10. Review
  11. Observational
  12. Article
  13. Article
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  15. Article
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Archit V PotharazuCollege of Medicine, University of Illinois at Chicago, Chicago, IL, USA.ORCID https://orcid.org/0000-0001-5613-5834
Antonio GangemiDepartment of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Policlinico Sant'Orsola IRCCS, Bologna, Italy.ORCID https://orcid.org/0000-0001-6381-3728
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITUniversity of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndocyanine green fluorescence (ICG-F) stains hepatic tumours and delineates vascular and biliary structures in real-time. We detail the efficacy of ICG-F in robotic hepatobiliary surgery.

methodsPubMed, EMBASE, Web of Science, and Cochrane Central were searched for original articles and meta-analyses detailing the outcomes of ICG-F in robotic hepatobiliary surgery.

results214 abstracts were reviewed; 16 studies are presented. One single-institution study reported ICG-F in robotic right hepatectomy reduced postoperative bile leakage (0% vs. 12%, p = 0.023), R1 resection (0% vs. 16%, p = 0.019), and readmission (p = 0.023) without prolonging operative time (288 vs. 272 min, p = 0.778). Improved visualisation aided in attainment of R0 resection in partial hepatectomies and radical gallbladder adenocarcinoma resections. Fewer ICG-F-aided robotic cholecystectomies were converted to open procedure compared to laparoscopic cholecystectomies (2.1% vs. 8.9%, p = 0.03; 0.15% vs. 2.6%, p < 0.001).

conclusionsICG-F improves clinical outcomes in robotic hepatobiliary surgery without prolonging operative time. There is an opportunity to standardise ICG administration protocols, especially for hepatectomies.

Indexed as

Indocyanine GreenRobotic Surgical ProceduresColoring AgentsFluorescenceHepatectomyHumansColoring AgentsIndocyanine Greenabdominalcholecystectomydigestive systemfluorescencegall bladdergeneral surgeryhepatectomyhepatobiliaryimaged guided surgeryintraoperative imagingliverminimal invasive surgerytumour

Identifiers

PMID36417426
PMCPMC10078519
OpenAlexW4309859292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.