Evidence map›Paper›PMID 36417198›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2023

Preserved peak exercise capacity in Andean highlanders with excessive erythrocytosis both before and after isovolumic hemodilution.

Cecilia Anza-Ramírez, Wanjun Gu, José L Macarlupú, Rómulo J Figueroa-Mujíca, Gustavo A Vizcardo-Galindo, Erica C Heinrich, Michael S Tift, Harrieth E Wagner, Peter D Wagner, Tatum S Simonson and 1 more

Abstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Altitude hypoxia and hypoxemia: pathogenesis and management.Signal transduction and targeted therapy · 2026
    Review
  6. Altitude illnesses.Nature reviews. Disease primers · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cecilia Anza-RamírezFacultad de Ciencias y Filosofía, Laboratorio de Fisiología Comparada/Laboratorio de Fisiología del Transporte de Oxígeno, Universidad Peruana Cayetano Heredia, Lima, Perú.
Wanjun GuDivision of Pulmonary, Critical Care, and Sleep Medicine, School of Medicine, University of California San Diego, La Jolla, California.
José L MacarlupúFacultad de Ciencias y Filosofía, Laboratorio de Fisiología Comparada/Laboratorio de Fisiología del Transporte de Oxígeno, Universidad Peruana Cayetano Heredia, Lima, Perú.
Rómulo J Figueroa-MujícaFacultad de Ciencias y Filosofía, Laboratorio de Fisiología Comparada/Laboratorio de Fisiología del Transporte de Oxígeno, Universidad Peruana Cayetano Heredia, Lima, Perú.
Gustavo A Vizcardo-GalindoFacultad de Ciencias y Filosofía, Laboratorio de Fisiología Comparada/Laboratorio de Fisiología del Transporte de Oxígeno, Universidad Peruana Cayetano Heredia, Lima, Perú.
Erica C HeinrichDivision of Pulmonary, Critical Care, and Sleep Medicine, School of Medicine, University of California San Diego, La Jolla, California.ORCID 0000-0002-6861-6165
Michael S TiftDivision of Pulmonary, Critical Care, and Sleep Medicine, School of Medicine, University of California San Diego, La Jolla, California.
Harrieth E WagnerDivision of Pulmonary, Critical Care, and Sleep Medicine, School of Medicine, University of California San Diego, La Jolla, California.
Peter D WagnerDivision of Pulmonary, Critical Care, and Sleep Medicine, School of Medicine, University of California San Diego, La Jolla, California.ORCID 0000-0001-7957-7432
Tatum S SimonsonDivision of Pulmonary, Critical Care, and Sleep Medicine, School of Medicine, University of California San Diego, La Jolla, California.
Francisco C VillafuerteFacultad de Ciencias y Filosofía, Laboratorio de Fisiología Comparada/Laboratorio de Fisiología del Transporte de Oxígeno, Universidad Peruana Cayetano Heredia, Lima, Perú.ORCID 0000-0003-0731-8911

Funding

Respiratory and genomic contributions to adaptive/maladaptive hypoxia responsesR01HL145470 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIMONSON, TATUM S · 2019 to 2023
$2.4M
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL145470NHLBI NIH HHS R01 HL145470Wellcome Trust (WT) 107544/Z/15/Z
6 · The paper itself

Abstract

In chronic mountain sickness (CMS), increased blood oxygen (O

Indexed as

Altitude SicknessPolycythemiaAltitudeExercise ToleranceHemodilutionHumansMaleOxygenOxygen ConsumptionOxygenAndean highlanderschronic mountain sicknessexcessive erythrocytosisexercise capacityisovolumic hemodilution

Identifiers

PMID36417198
PMCPMC9762978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.