Evidence map›Paper›PMID 36417038›Full record

ArticleBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine2023

Haemodialysis alters the serum metal contents in chronic kidney failure patients at hyderabad and adjoining areas.

Marvi Shaikh, Naseem Aslam Channa, Ali Muhammad Wahryah, Muhammad Haneef Mugheri, Shakil Samejo, Lubna Noorani

Abstract read
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Article in Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Analysis of serum lead, copper, iron, and zinc and hematological parameters in battery smelting workers: assessing lead toxicity.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marvi ShaikhInstitute of Biochemistry, University of Sindh, Jamshoro, 76090, Sindh, Pakistan.
Naseem Aslam ChannaInstitute of Biochemistry, University of Sindh, Jamshoro, 76090, Sindh, Pakistan. nachanna2000@gmail.com.ORCID http://orcid.org/0000-0003-0629-4209
Ali Muhammad WahryahMolecular Biology and Genetics Department, Liaquat University of Medical Health Sciences, Jamshoro, Pakistan.
Muhammad Haneef MugheriInstitute of Biochemistry, University of Sindh, Jamshoro, 76090, Sindh, Pakistan.
Shakil SamejoInstitute of Chest Diseases, Bilawal Medical College, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Lubna NooraniDepartment of Science and Technical Education, Faculty of Education, Elsa Kazi Campus, Hyderabad, Pakistan.
University of Sindh · PKLiaquat University of Medical & Health Sciences · PKUniversity of Education · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Present study aimed to explore alterations of serum metal contents in patients of chronic kidney disease before and after haemodialysis (HD) compared to controls. For the levels of heavy metals in serum samples of kidney patients before and after HD belonging to different areas of Hyderabad and adjoining areas admitted at different hospitals of Hyderabad. In this study, the level of copper (Cu), zinc (Zn), chromium (Cr), iron (Fe) and manganese (Mn) in serum sample of kidney patients and controls have been investigated using Atomic Absorption Spectrophotometer (AAS). An increase in serum urea and serum creatinine levels in patients with chronic kidney disease (CKD) when compared to controls was observed and it was due to the decreased glomerular filtration in patients with CKD. The average of serum Cu and Cr were significantly high in pre-HD patients as compared to controls, reverse was found just in case of Mn and Fe. Serum Cu and Mn were significantly increased in post-HD patients when put next to the controls, whereas, serum Cr concentration was significantly decreased after HD in comparison to the controls. Concentration of serum Cu, Fe and Mn were significantly increased in post-HD patients as compared to the pre-HD patients. In conclusion, hemodialysis alters the serum metal contents in CKD patients. After the study, it is suggested that, serum metal contents before the dialysis session must be investigated more extensively to elucidate the alterations throughout the dialysis session and may be medicated accordingly.

Indexed as

Kidney Failure, ChronicMetals, HeavyRenal Insufficiency, ChronicTrace ElementsChromiumHumansManganeseRenal DialysisChromiumManganeseMetals, HeavyTrace ElementsCKDCreatinineESRDPre and post-HD patients’ ureaSerum metals

Identifiers

PMID36417038
OpenAlexW4309700041

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.