ArticlePerfusion2023
Enabling the control of reperfusion parameters in out-of-hospital cardiac arrest: First applications of the CARL system.
Article in Perfusion, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Ethics in prehospital extracorporeal cardiopulmonary resuscitation.Resuscitation plus · 2026Article
- Immediate post-ECPR management strategies in the prehospital and critical care transport medicine environments.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025Review
- Impact of prehospital extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest on survival with good neurological function: a systematic review and meta-analysis.Resuscitation plus · 2025Review
- Contemporary Practices in Refractory Out-of-Hospital Cardiac Arrest: A Narrative Review.Medicina (Kaunas, Lithuania) · 2025Review
- Database and geospatial mapping study of those eligible for extracorporeal cardiopulmonary resuscitation in the Thames Valley Region, England.Resuscitation plus · 2025Article
- A training programme for novice extracorporeal resuscitation providers.Resuscitation plus · 2024Article
- Extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest: 10-year experience in a metropolitan cardiac arrest centre in Milan, Italy.Resuscitation plus · 2024Article
- Treatment of Refractory Cardiac Arrest by Controlled Reperfusion of the Whole Body: A Multicenter, Prospective Observational Study.Journal of clinical medicine · 2023Article
- Extracorporeal Cardiopulmonary Resuscitation.Deutsches Arzteblatt international · 2023Review
- Effects of Prolonged Serum Calcium Suppression during Extracorporeal Cardiopulmonary Resuscitation in Pigs.Biomedicines · 2023Article
- Development of anFrontiers in medicine · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThere is increasing evidence for extracorporeal cardiopulmonary resuscitation (ECPR) as a rescue therapy for selected patients in refractory cardiac arrest (CA). Besides patient selection, the control of reperfusion parameters is of eminent importance. Especially in out-of-hospital CA, monitoring and individualized, targeted reperfusion remains a great challenge for emergency personnel. The CARL® system is designed to enable an early control of a variety of reperfusion parameters and to pursue a targeted reperfusion strategy in ECPR. CASE PRESENTATION: We report the first 10 ECPR applications of the CARL® system in Regensburg, Germany. Early blood gas analysis, oxygen titration and pressure monitoring were feasible and enabled an individualized and targeted reperfusion strategy in all patients. After suffering from refractory CA and prolonged resuscitation attempts, five out of the first 10 patients survived and were successfully discharged from the hospital (CPC one on hospital discharge).
conclusionApplication of the CARL® system contributed to early monitoring and control of reperfusion parameters. Whether targeted ECPR may have the potential to improve outcomes in refractory OHCA remains the subject of future investigations.
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