Evidence map›Paper›PMID 36416677›Full record

ArticleLeukemia & lymphoma2023

Psychosocial characteristics of patients undergoing cellular immunotherapies and their caregivers across time.

Kedar Kirtane, Maija Reblin, Laura B Oswald, Nathaly Irizarry-Arroyo, Rachael McCormick, Frederick L Locke, Dana Ketcher

Open access · greenAbstract read
In one paragraph

Article in Leukemia & lymphoma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kedar KirtaneDepartment of Head and Neck-Endocrine Oncology, Moffitt Cancer Center, Tampa, FL, USA.ORCID 0000-0003-1302-9577
Maija ReblinDepartment of Family Medicine, University of Vermont, Burlington, VT, USA.ORCID 0000-0003-3108-465X
Laura B OswaldDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.ORCID 0000-0001-6281-2512
Nathaly Irizarry-ArroyoDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Rachael McCormickDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.ORCID 0000-0003-2794-9921
Frederick L LockeDepartment of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL, USA.ORCID 0000-0001-9063-6691
Dana KetcherUniversity of Minnesota Medical School, Duluth Campus, MN, USA.ORCID 0000-0003-3569-9344
Moffitt Cancer Center · USUniversity of Minnesota, Duluth · USUniversity of Vermont · US

Funding

ECOG-ACRIN NCORP Research Base - TMISTUG1CA189828 · NCI · ECOG-ACRIN MEDICAL RESEARCH FOUNDATION · PI Peter J ODwyer, MITCHELL D. SCHNALL · 2014 to 2026
$199.7M
NCI NIH HHS UG1 CA189828
6 · The paper itself

Abstract

Chimeric antigen receptor T-cells and other immunotherapies have markedly changed the paradigm of treatment for patients with relapsed or refractory hematologic malignancies. While notable in efficacy, immunotherapy is characterized by a significant possibility of life-threatening side effects. Consequently, patients are often required to have informal family caregivers present and to stay near the treating center for several weeks after cell infusion. Further, the responsibility of managing a great deal of physical care and emotional support falls to these caregivers. Given the novelty of immunotherapy treatment, there is a need to better understand the psychosocial experience of patients receiving this treatment and their caregivers. This article describes the psychosocial characteristics of patients undergoing cellular immunotherapies and their caregivers across time, including patient/caregiver distress, coping, and caregiver burden and preparedness.

Indexed as

CaregiversHematologic NeoplasmsAdaptation, PsychologicalHumansImmunotherapyQuality of LifecancercaregiverCAR-Tcellular immunotherapypsychosocial

Identifiers

PMID36416677
PMCPMC10329860
OpenAlexW4309830166

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.