Evidence map›Paper›PMID 36416376›Full record

ReviewEmerging topics in life sciences2022

The bed nucleus of the stria terminalis in threat detection: task choice and rodent experience.

Emily R Sherman, Jasmine J Thomas, Emma N Cahill

Abstract readReview
In one paragraph

Review in Emerging topics in life sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emily R ShermanDepartment of Physiology, Development and Neuroscience, University of Cambridge, Bristol CB2 3EB, U.K.
Jasmine J ThomasDepartment of Physiology, Development and Neuroscience, University of Cambridge, Bristol CB2 3EB, U.K.
Emma N CahillDepartment of Physiology, Development and Neuroscience, University of Cambridge, Bristol CB2 3EB, U.K.ORCID 0000-0003-3054-1708

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Behavioural reactivity to potential threat is used to experimentally refine models of anxiety symptoms in rodents. We present a short review of the literature tying the most commonly used tasks to model anxiety symptoms to functional recruitment of bed nucleus of the stria terminalis circuits (BNST). Using a review of studies that investigated the role of the BNST in anxiety-like behaviour in rodents, we flag the certain challenges for the field. These stem from inconsistent methods of reporting the neuroanatomical BNST subregions and the interpretations of specific behaviour across a wide variety of tasks as 'anxiety-like'. Finally, to assist in interpretation of the findings, we discuss the potential interactions between typically used 'anxiety' tasks of innate behaviour that are potentially modulated by the social and individual experience of the animal.

Indexed as

RodentiaSeptal NucleiAnimalsanxietybed nucleus stria terminalisbehaviourfearmouserat

Identifiers

PMID36416376
PMCPMC9788396

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.