Evidence map›Paper›PMID 36416312›Full record

ArticleOncology reports2023

Neuroprotective and anticancer effects of 7‑Methoxyheptaphylline via the TAK1 pathway.

Chantana Boonyarat, Mongkhonphan Tantiwatcharakunthon, Pitchayakarn Takomthong, Chavi Yenjai, Yoshihiro Hayakawa, Pornngarm Dejkriengkraikul, Suchada Chaiwiwatrakul, Pornthip Waiwut

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Anticancer Effects ofInternational journal of molecular sciences · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Chantana BoonyaratFaculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Mongkhonphan TantiwatcharakunthonFaculty of Pharmaceutical Sciences, Ubon Ratchathani University, Ubon Ratchathani 34190, Thailand.
Pitchayakarn TakomthongFaculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Chavi YenjaiNatural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Yoshihiro HayakawaSection of Host Defences, Institute of Natural Medicine, University of Toyama, Toyama 930‑0194, Japan.
Pornngarm DejkriengkraikulDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Suchada ChaiwiwatrakulDepartment of English, Faculty of Humanities and Social Sciences, Ubon Ratchathani Rajabhat University, Ubon Ratchathani 34000, Thailand.
Pornthip WaiwutFaculty of Pharmaceutical Sciences, Ubon Ratchathani University, Ubon Ratchathani 34190, Thailand.
Khon Kaen University · THUbon Ratchathani University · THChiang Mai University · THUbon Ratchathani Rajabhat University · THUniversity of Toyama · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

7‑Methoxyheptaphylline (7‑MH) is a carbazole extracted from

Indexed as

Hydrogen PeroxideNeuroblastomaAnimalsCarbazolesCaspase 3Cell Line, TumorGlycogen Synthase Kinase 3HumansMolecular Docking Simulation7-methoxyheptaphyllineCarbazolesCaspase 3Glycogen Synthase Kinase 3Hydrogen Peroxide7‑methoxyheptaphyllineapoptosiscancerClausena harmandianaglycogen synthase kinase‑3neuron cellsTGF‑β‑activated kinase 1

Identifiers

PMID36416312
PMCPMC9713861
OpenAlexW4309766754

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.