Evidence map›Paper›PMID 36416008›Full record

ReviewMicrobial biotechnology2023

Biological and technical challenges for implementation of yeast-based biosensors.

Ehtisham Wahid, Ohiemi Benjamin Ocheja, Enrico Marsili, Cataldo Guaragnella, Nicoletta Guaragnella

Abstract readReview
In one paragraph

Review in Microbial biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Mining Genetically Encoded Biosensors from Filamentous Fungi.Journal of fungi (Basel, Switzerland) · 2026
    Review
  4. Review
  5. Special Issue: "Yeast as a Model System to Study Human Diseases".International journal of molecular sciences · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ehtisham WahidDEI - Department of Electrical and Information Engineering - Politecnico di Bari, Bari, Italy.
Ohiemi Benjamin OchejaDepartment of Biosciences, Biotechnologies and Environment - University of Bari "A. Moro", Bari, Italy.
Enrico MarsiliNottingham Ningbo China Beacons of Excellence Research and Innovation Institute, Ningbo, China.
Cataldo GuaragnellaDEI - Department of Electrical and Information Engineering - Politecnico di Bari, Bari, Italy.
Nicoletta GuaragnellaDepartment of Biosciences, Biotechnologies and Environment - University of Bari "A. Moro", Bari, Italy.ORCID 0000-0002-3880-777X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biosensors are low-cost and low-maintenance alternatives to conventional analytical techniques for biomedical, industrial and environmental applications. Biosensors based on whole microorganisms can be genetically engineered to attain high sensitivity and specificity for the detection of selected analytes. While bacteria-based biosensors have been extensively reported, there is a recent interest in yeast-based biosensors, combining the microbial with the eukaryotic advantages, including possession of specific receptors, stability and high robustness. Here, we describe recently reported yeast-based biosensors highlighting their biological and technical features together with their status of development, that is, laboratory or prototype. Notably, most yeast-based biosensors are still in the early developmental stage, with only a few prototypes tested for real applications. Open challenges, including systematic use of advanced molecular and biotechnological tools, bioprospecting, and implementation of yeast-based biosensors in electrochemical setup, are discussed to find possible solutions for overcoming bottlenecks and promote real-world application of yeast-based biosensors.

Indexed as

Biosensing TechniquesSaccharomyces cerevisiaeBacteriaBiotechnologyElectrochemical TechniquesGenetic Engineering

Identifiers

PMID36416008
PMCPMC9803330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.