Evidence map›Paper›PMID 36415998›Full record

ArticleObesity (Silver Spring, Md.)2022

Replacing sedentary time with light activity was associated with less adiposity across several depots in African ancestry men.

Megan M Marron, Ryan K Cvejkus, Adrianna I Acevedo-Fontanez, Allison L Kuipers, Sangeeta Nair, John Jeffrey Carr, James G Terry, Victor Wheeler, Iva Miljkovic

Open access · greenAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Megan M MarronDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-9561-3966
Ryan K CvejkusDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-5287-5341
Adrianna I Acevedo-FontanezDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-0107-5170
Allison L KuipersDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-1415-1742
Sangeeta NairDepartment of Radiology & Radiological Sciences, Vanderbilt University Medicine Center, Nashville, Tennessee, USA.
John Jeffrey CarrDepartment of Radiology & Radiological Sciences, Vanderbilt University Medicine Center, Nashville, Tennessee, USA.ORCID 0000-0002-4398-8237
James G TerryDepartment of Radiology & Radiological Sciences, Vanderbilt University Medicine Center, Nashville, Tennessee, USA.ORCID 0000-0001-6659-3441
Victor WheelerTobago Health Studies Office, Scarborough, Trinidad and Tobago.
Iva MiljkovicDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-3155-9777
University of Pittsburgh · USVanderbilt University · USUniversity of Trinidad and Tobago · TT

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
Cardiovascular Epidemiology Training ProgramT32HL083825 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AKIRA SEKIKAWA · 2008 to 2026
$6.1M
Epidemiology of Bone Loss in African MenR01AR049747 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZMUDA, JOSEPH M. · 2003 to 2014
$5.9M
Epidemiology of Obesity, Diabetes, and Hypertension in African CaribbeansR01HL143793 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MILJKOVIC, IVA · 2018 to 2021
$2.7M
Ectopic adiposity in black men with high type 2 diabetes riskR01DK097084 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MILJKOVIC, IVA · 2013 to 2016
$1.9M
Association of Type 2 Diabetes with Liver and Muscle Adiposity in Black MenR03DK092348 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MILJKOVIC, IVA · 2011 to 2012
$163k
NHLBI NIH HHS R01 HL143793NHLBI NIH HHS T32 HL083825NIAMS NIH HHS R01 AR049747NIA NIH HHS P30 AG024827NIDDK NIH HHS R01 DK097084NIDDK NIH HHS R03 DK092348
6 · The paper itself

Abstract

objectiveThe aim of this study was to determine whether displacement of sedentary time with activity was cross-sectionally associated with less adiposity among Black Caribbean men in the Tobago Health Study.

methodsObjectively assessed activity was categorized as sedentary (< 1.5 metabolic equivalents; METs), light (≥ 1.5 to < 3.0 METs), or moderate-to-vigorous (≥ 3.0 METs) using the SenseWear Pro armband. Computed tomography scans of the chest, abdomen, liver, and thigh were used to assess subcutaneous and ectopic adipose tissue. The isotemporal substitution framework paired with linear regression was used to examine associations between activity and adiposity adjusting for age, height, total awake time, and multiple comparisons.

resultsOn average, participants (n = 271) were 63 years old with 11.2 h/d of sedentary behavior, 4.5 h/d of light activity, and 54 min/d of moderate-to-vigorous activity. Replacing sedentary time with light activity was cross-sectionally associated with lower volume and higher density of abdominal and thigh subcutaneous adiposity, visceral adiposity, abdominal and thigh intermuscular adiposity, and pericardial adiposity and higher liver attenuation (p values ≤ 0.0001).

conclusionsDisplacement of sedentary time with light activity was associated with less adiposity among this Black Caribbean cohort. Interventions focused on increasing light activity may be easier to maintain than higher intensity interventions and thus may be more successful at reducing adiposity.

Indexed as

AdipositySedentary BehaviorBlack PeopleExerciseHumansMaleMiddle AgedObesity

Identifiers

PMID36415998
PMCPMC9832382
OpenAlexW4309724001

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.