Evidence map›Paper›PMID 36415964›Full record

ArticleJournal of the American Geriatrics Society2023

Racial disparities among older adults with acute myocardial infarction: The SILVER-AMI study.

Patrick C Demkowicz, Alexandra M Hajduk, John A Dodson, Carol R Oladele, Sarwat I Chaudhry

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Racial and socioeconomic disparities in postoperative outcomes following coronary artery bypass grafting: a national inpatient analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Patrick C DemkowiczDepartment of Internal Medicine, Section of General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0002-9566-1033
Alexandra M HajdukDepartment of Internal Medicine, Section of Geriatrics, Yale University School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0002-5800-347X
John A DodsonDepartment of Medicine, Division of Cardiology, NYU Grossman School of Medicine, New York, New York, USA.
Carol R OladeleDepartment of Internal Medicine, Section of General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Sarwat I ChaudhryDepartment of Internal Medicine, Section of General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Yale University · USNew York University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Albert C Shaw · 2002 to 2026
$37.9M
Risk Stratification in Older Persons with Acute Myocardial Infarction: SILVER-AMIR01HL115295 · NHLBI · YALE UNIVERSITY · PI CHAUDHRY, SARWAT I · 2012 to 2016
$11.3M
Short-Term Reserch Training: Students in Health SchoolsT35HL007649 · NHLBI · YALE UNIVERSITY · PI Sarwat I Chaudhry, Erica L Herzog · 1987 to 2026
$5.7M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL115295NHLBI NIH HHS T35 HL007649NIA NIH HHS P30 AG021342
6 · The paper itself

Abstract

backgroundDespite an aging population, little is known about racial disparities in aging-specific functional impairments and mortality among older adults hospitalized for acute myocardial infarction (AMI).

methodsWe analyzed data from patients aged 75 years or older who were hospitalized for AMI at 94 US hospitals from 2013 to 2016. Functional impairments and geriatric conditions were assessed in-person during the AMI hospitalization. The association between race and risk of mortality (primary outcome) was evaluated with logistic regression adjusted sequentially for age, clinical characteristics, and measures of functional impairment and other conditions associated with aging.

resultsAmong 2918 participants, 2668 (91.4%) self-identified as White and 250 (8.6%) as Black. Black participants were younger (80.8 vs 81.7 years; p = 0.010) and more likely to be female (64.8% vs 42.5%; p < 0.001). Black participants were more likely to present with impairments in cognition (37.6% vs 14.5%; p < 0.001), mobility (66.0% vs 54.6%; p < 0.001) and vision (50.1% vs 35.7%; p < 0.001). Black participants were also more likely to report a disability in one or more activities of daily living (22.4% vs 13.0%; p < 0.001) and an unintentional loss of more than 10 lbs in the year prior to hospitalization (37.2% vs 13.0%; p < 0.001). The unadjusted odds of 6-month mortality among Black participants (odds ratio [OR] 2.0, 95% confidence interval [CI] 1.4-2.8) attenuated to non-significance after adjustment for age, clinical characteristics (OR 1.70, 95% CI 1.7, 1.2-2.5), and functional/geriatric conditions (OR 1.5, 95% CI 1.0-2.2).

conclusionsBlack participants had a more geriatric phenotype despite a younger average age, with more functional impairments. Controlling for functional impairments and geriatric conditions attenuated disparities in 6-month mortality somewhat. These findings highlight the importance of systematically assessing functional impairment during hospitalization and also ensuring equitable access to community programs to support post-AMI recovery among Black older adults.

Indexed as

Activities of Daily LivingHealth Status DisparitiesMyocardial InfarctionBlack or African AmericanFemaleHospitalizationHospitalsHumansMaleUnited StatesWhiteacute myocardial infarctionBlack/African Americanfunctional impairmenthealth care disparitiesrace

Identifiers

PMID36415964
PMCPMC9957871
OpenAlexW4309724053

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.