Evidence map›Paper›PMID 36415834›Full record

ReviewAsian journal of pharmaceutical sciences2022

Liposomes and liposome-like nanoparticles: From anti-fungal infection to the COVID-19 pandemic treatment.

Yonglong He, Wanting Zhang, Qingqing Xiao, Lifang Fan, Dechun Huang, Wei Chen, Wei He

Open access · diamondAbstract readReview
In one paragraph

Review in Asian journal of pharmaceutical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yonglong HeSchool of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
Wanting ZhangSchool of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
Qingqing XiaoSchool of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
Lifang FanJiangsu Aosaikang Pharmaceutical Co., Ltd., Nanjing 211112, China.
Dechun HuangSchool of Engineering, China Pharmaceutical University, Nanjing 210009, China.
Wei ChenSchool of Engineering, China Pharmaceutical University, Nanjing 210009, China.
Wei HeShanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200443, China.
China Pharmaceutical University · CNKanion Pharmaceutical (China) · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The liposome is the first nanomedicine transformed into the market and applied to human patients. Since then, such phospholipid bilayer vesicles have undergone technological advancements in delivering small molecular-weight compounds and biological drugs. Numerous investigations about liposome uses were conducted in different treatment fields, including anti-tumor, anti-fungal, anti-bacterial, and clinical analgesia, owing to liposome's ability to reduce drug cytotoxicity and improve the therapeutic efficacy and combinatorial delivery. In particular, two liposomal vaccines were approved in 2021 to combat COVID-19. Herein, the clinically used liposomes are reviewed by introducing various liposomal preparations in detail that are currently proceeding in the clinic or on the market. Finally, we discuss the challenges of developing liposomes and cutting-edge liposomal delivery for biological drugs and combination therapy.

Indexed as

Clinical applicationCOVID-19 pandemicDrug deliveryLiposomes

Identifiers

PMID36415834
PMCPMC9671608
OpenAlexW4309634888

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.