Evidence map›Paper›PMID 36415764›Full record

ArticleThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG2022

Health Economics of Selective Early Rescue Surfactant Administration and Standard Surfactant Administration for Newborns With Respiratory Distress Syndrome.

Weiyu Yao, Ivar Jensen, Marc Claussen, Kristen Dandurand, Brandy Buffington, Daniel Fuentes, Michel Mikhael

Open access · bronzeAbstract read
In one paragraph

Article in The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Effects of a respiratory care protocol incorporating less invasive surfactant administration in infants born at 30-34 weeks' gestation.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  2. Article
  3. Outcomes, safety and health economics of introduction of video laryngoscopy-assisted less invasive surfactant administration.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Weiyu YaoPRECISIONheor (WY and IJ), Boston, MA.
Ivar JensenPRECISIONheor (WY and IJ), Boston, MA.
Marc ClaussenChiesi USA Inc (MC, KD, BB, DF), Cary, NC.
Kristen DandurandChiesi USA Inc (MC, KD, BB, DF), Cary, NC.
Brandy BuffingtonChiesi USA Inc (MC, KD, BB, DF), Cary, NC.
Daniel FuentesChiesi USA Inc (MC, KD, BB, DF), Cary, NC.
Michel MikhaelNeonatal-Perinatal Medicine Division (MM), Children's Hospital of Orange County, Orange, CA.
Chiesi (United States) · USChildren's Hospital of Orange County · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo quantify the effect of early rescue surfactant administration techniques for preterm infants with respiratory distress syndrome (RDS) from a health care delivery system perspective.

methodsA cost-consequence model was developed based on previously published literature to compare the health economic impact of implementing early surfactant administration strategies vs standard surfactant administration via endotracheal intubation and mechanical ventilation (MV).

resultsEarly rescue surfactant treatment strategies are associated with a decrease in the number of patients requiring MV, cumulative MV days, and rate of neonatal complications. Total annual surfactant costs are higher than standard surfactant administration, but this is offset by savings in total hospital and complication costs.

conclusionsThis cost-consequence analysis suggests selective early rescue surfactant administration strategies are associated with a lower health care burden in premature infants with RDS.

Indexed as

bronchopulmonary dysplasiacost-consequence analysishealth economicsintubate surfactant extubateless invasive surfactant administrationpremature infantsrespiratory distress syndrome

Identifiers

PMID36415764
PMCPMC9674362
OpenAlexW4309218731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.