Evidence map›Paper›PMID 36415737›Full record

ArticleAccess microbiology2022

Post-operative antibiotics for cutaneous abscess after incision and drainage: Variations in clinical practice.

Michael El Boghdady, Béatrice Marianne Ewalds-Kvist, Sarah Zhao, Ahmad Najdawi, Aggelos Laliotis

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Access microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07704359 (Randomized Antibiotics for Prevention of Fistula After Incision and Drainage of First-Episode Perianal Abscess), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07704359 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Randomized Antibiotics for Prevention of Fistula After Incision and Drainage of First-Episode Perianal Abscess (RAPID): A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of Illinois at ChicagoRan2026 to 2029Enrolled236ConditionsPerianal Abscess, Anal FistulaArmsAmoxicillin + Clavulanate, Ciprofloxacin + Metronidazole
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Low Adherence to Prophylactic Antibiotics and Surgical Site Infection.Iranian journal of nursing and midwifery research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Michael El BoghdadyDepartment of General Surgery, Croydon University Hospital, London, UK.ORCID https://orcid.org/0000-0001-9542-695X
Béatrice Marianne Ewalds-KvistStockholm University, Stockholm, Sweden.
Sarah ZhaoDepartment of General Surgery, Croydon University Hospital, London, UK.
Ahmad NajdawiDepartment of General Surgery, Croydon University Hospital, London, UK.
Aggelos LaliotisDepartment of General Surgery, Croydon University Hospital, London, UK.
Croydon University Hospital · GBSt George's, University of London · GBUniversity of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute cutaneous abscess is a common surgical condition that mostly requires incision and drainage. Despite this, there is no standardized national or international guidance on post-operative antibiotics prescription. Traditionally, antibiotics are not indicated unless complications and/or risk factors such as immunocompromisation, diabetes or cellulitis exist. We aimed to study the local practice for post-operative antibiotics prescription for cutaneous abscesses in a UK university teaching hospital. Methods: Retrospective data collection for emergency general surgical admissions for a period of 6 months was carried out. All patients with cutaneous abscesses were included in this analysis. Scrotal, breast and limb abscesses were excluded. Patients' demographics, co-morbidities and complications, including local (cellulitis, necrosis) and systemic (e.g sepsis), were studied. Approval for access to patient data was granted by the local clinical governance department prior to the commencement of this study. Computations were performed using IBM SPSS version 26. Chi square ( Results: A total of 148 patients were included. The mean age was 40 years (55 % males). The most common site of abscess was perianal (27.7 %), followed by pilonidal (20.3 %) and axilla (16.9 %). A total of 107 (73 %) were managed surgically with incision and drainage, and of these 92 (86 %) were managed within 24 h. Altogether, 83 (76 %) were prescribed post-operative antibiotics, while only 25 (23 %) had indications. The most used post-operative empirical antibiotics was co-amoxiclav (59 %). There was a significant relationship between 'abscess site' × 'antibiotics' [ Conclusions: There were variations in clinical practice regarding post-operative antibiotic prescription for cutaneous abscesses. Research is required in the future in cooperation with microbiologists to develop a standardized evidence-based treatment protocol for the management of such a common surgical condition.

Indexed as

AntibioticsCutaneous abscessIncision and drainageMicroguidelines

Identifiers

PMID36415737
PMCPMC9675173
OpenAlexW4307472579

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.