Evidence map›Paper›PMID 36415660›Full record

ArticleBrain communications2022

Thirty novel sequence variants impacting human intracranial volume.

Muhammad Sulaman Nawaz, Gudmundur Einarsson, Mariana Bustamante, Rosa S Gisladottir, G Bragi Walters, Gudrun A Jonsdottir, Astros Th Skuladottir, Gyda Bjornsdottir, Sigurdur H Magnusson, Bergrun Asbjornsdottir and 17 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 3 institutions in 1 country.

Muhammad Sulaman NawazdeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
Gudmundur EinarssondeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
Mariana BustamantedeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
Rosa S GisladottirdeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
G Bragi WaltersdeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
Gudrun A JonsdottirdeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
Astros Th SkuladottirdeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.ORCID https://orcid.org/0000-0002-5048-0933
Gyda BjornsdottirdeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
Sigurdur H MagnussondeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
Bergrun AsbjornsdottirdeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
Unnur UnnsteinsdottirdeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
Engilbert SigurdssonFaculty of Medicine, School of Health Sciences, University of Iceland, Vatnsmyrarvegur 16, 101 Reykjavik, Iceland.
Palmi V JonssonFaculty of Medicine, School of Health Sciences, University of Iceland, Vatnsmyrarvegur 16, 101 Reykjavik, Iceland.
Vala Kolbrun PalmadottirDepartment of Internal Medicine, Landspitali University Hospital, Hringbraut 101, 101 Reykjavik, Iceland.
Sigurjon A GudjonssondeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
Gisli H HalldorssondeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
Egil FerkingstaddeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.ORCID https://orcid.org/0000-0001-8090-7988
Ingileif JonsdottirdeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.ORCID https://orcid.org/0000-0001-8339-150X
Gudmar ThorleifssondeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.ORCID https://orcid.org/0000-0003-4623-9087
Hilma HolmdeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.ORCID https://orcid.org/0000-0002-9517-6636
Unnur ThorsteinsdottirdeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.ORCID https://orcid.org/0000-0002-7049-2827
Patrick SulemdeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.ORCID https://orcid.org/0000-0001-7123-6123
Daniel F GudbjartssondeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
Hreinn StefanssondeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.ORCID https://orcid.org/0000-0002-9331-6666
Thorgeir E ThorgeirssondeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.ORCID https://orcid.org/0000-0002-5149-7040
Magnus O UlfarssondeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.
Kari StefanssondeCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.ORCID https://orcid.org/0000-0003-1676-864X
deCODE Genetics (Iceland) · ISUniversity of Iceland · ISNational University Hospital of Iceland · IS

Funding

Medical Research Council MC_PC_17228Medical Research Council MC_QA137853
6 · The paper itself

Abstract

Intracranial volume, measured through magnetic resonance imaging and/or estimated from head circumference, is heritable and correlates with cognitive traits and several neurological disorders. We performed a genome-wide association study meta-analysis of intracranial volume (

Indexed as

brain structuregenetic correlationgenome-wide association studyintracranial volumeMendelian randomization

Identifiers

PMID36415660
PMCPMC9677475
OpenAlexW4307386054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.