Evidence map›Paper›PMID 36415563›Full record

ArticleHealth science reports2022

Comparison of visfatin levels in patients with breast cancer and endometrial cancer with healthy individuals: A systematic review and meta-analysis.

Hori Ghaneialvar, Samira Shiri, Azra Kenarkoohi, Zahra Fallah Vastani, Alireza Ahmadi, Ali Khorshidi, Roghayeh Khooz

Open access · goldAbstract read
In one paragraph

Article in Health science reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Breast cancer shares many epidemiological, lifestyle, and local hormonal and metabolic underpinnings with endometrial and ovarian cancer: a narrative review.Translational breast cancer research : a journal focusing on translational research in breast cancer · 2025
    Review
  2. Exploring the multifaceted role of obesity in breast cancer progression.Frontiers in cell and developmental biology · 2024
    Review
  3. Article
  4. Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hori GhaneialvarBiotechnology and Medicinal Plants Research Center Ilam University of Medical Sciences Ilam Iran.
Samira ShiriClinical Research Development Centre, Taleghani and Imam Ali Hospital Kermanshah University of Medical Sciences Kermanshah Iran.
Azra KenarkoohiZoonotic Diseases Research Center Ilam University of Medical Sciences Ilam Iran.ORCID 0000-0003-4077-9824
Zahra Fallah VastaniStudent Research Committee, Faculty of Allied Medical Sciences Ilam University of Medical Sciences Ilam Iran.ORCID 0000-0001-9369-8011
Alireza AhmadiStudent Research Committee, Faculty of Allied Medical Sciences Ilam University of Medical Sciences Ilam Iran.
Ali KhorshidiDepartment of Epidemiology, School of Medicine Ilam University of Medical Sciences Ilam Iran.
Roghayeh KhoozBiotechnology and Medicinal Plants Research Center Ilam University of Medical Sciences Ilam Iran.
Medical University of Ilam · IRKermanshah University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Endometrial cancer (EC) and breast cancer (BC) are prevalent in women. Visfatin is an adipokine that, in addition to being involved in metabolism and inflammation, may also be interested in carcinogenesis. Visfatin measurement in cancer patients has shown that visfatin levels in cancer patients differed from those in healthy subjects. Various studies have shown that the level of visfatin is increased in people within EC and BC, and this difference has a significant relationship with prognosis. Methods: A comprehensive search of related articles from PubMed, Scopus, Web of Science, and the Google Scholar database was done by November 2021. Eligible articles measured visfatin levels in patients with breast cancer and EC. After selecting the eligible studies, the data were extracted and analyzed using the random effect method. Results: Given the effect size and the confidence interval obtained, the total level of visfatin in cancer patients was different from that in healthy individuals, and this difference was statistically significant. However, the difference in visfatin levels in patients with breast cancer was much more significant than in patients with EC compared to the control group. Conclusions: Due to the significant increase in visfatin levels in these patients, visfatin may be a potential prognostic factor in breast and ECs. Visfatin levels in cancer patients differed from those in healthy subjects, and this difference was also statistically significant (

Indexed as

adipokinebreast cancer (BC)endometrial cancer (EC)neoplasmnicotinamide phosphoribosyltransferase (NAMPT)visfatin

Identifiers

PMID36415563
PMCPMC9674168
OpenAlexW4309306368

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.