Evidence map›Paper›PMID 36415550›Full record

ArticleRSC advances2022

Assessment of a host-guest interaction in a bilayer membrane model.

Harshita Kumari, Saeedeh Negin, Andrew Eisenhart, Mohit B Patel, Thomas L Beck, Frank Heinrich, Helena J Spikes, George W Gokel

Abstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Antimicrobial and Adjuvant Potencies of Di-Antibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Harshita KumariJames L. Winkle College of Pharmacy, University of Cincinnati Cincinnati Ohio USA 45267-0514 kumariha@ucmail.uc.edu.ORCID https://orcid.org/0000-0002-6861-0281
Saeedeh NeginChemistry & Biochemistry, University of Missouri-St. Louis 1 University Blvd. St. Louis MO 63121 USA gokelg@umsl.edu.
Andrew EisenhartDepartment of Chemistry, University of Cincinnati OH 45267 USA.
Mohit B PatelChemistry & Biochemistry, University of Missouri-St. Louis 1 University Blvd. St. Louis MO 63121 USA gokelg@umsl.edu.ORCID https://orcid.org/0000-0002-7164-4503
Thomas L BeckDepartment of Chemistry, University of Cincinnati OH 45267 USA.
Frank HeinrichDepartment of Physics, Carnegie Mellon University Pittsburgh PA 15213 USA.
Helena J SpikesChemistry & Biochemistry, University of Missouri-St. Louis 1 University Blvd. St. Louis MO 63121 USA gokelg@umsl.edu.
George W GokelChemistry & Biochemistry, University of Missouri-St. Louis 1 University Blvd. St. Louis MO 63121 USA gokelg@umsl.edu.ORCID https://orcid.org/0000-0003-3994-6795

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Supramolecular interactions are well recognized and many of them have been extensively studied in chemistry. The formation of supramolecular complexes that rely on weak force interactions are less well studied in bilayer membranes. Herein, a supported bilayer membrane is used to probe the penetration of a complex between tetracycline and a macrocyclic polyether. In a number of bacterial systems, the presence of the macrocycle has been found to significantly enhance the potency of the antimicrobial

Identifiers

PMID36415550
PMCPMC9648047

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.