Evidence map›Paper›PMID 36415512›Full record

ArticleJournal of medicine and life2022

Analysis of TERT Rs2736100 genotype distribution in laryngeal squamous cell carcinoma patients.

Corina Iulia Cornean, Alma Aurelia Maniu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicine and life, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Corina Iulia CorneanDepartment of Otolaryngology-Head and Neck Surgery, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Alma Aurelia ManiuDepartment of Otolaryngology-Head and Neck Surgery, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The applicability of the telomerase reverse transcriptase (TERT) gene Rs2736100 polymorphism in cancer research has been well documented for various malignancies except for head and neck cancers, where data is sparse. This study aimed to analyze this polymorphism with the pathological characterizers of laryngeal squamous cell carcinoma (LSCC) patients. Genetic testing was performed using the Real-time PCR technique on 56 paired samples of biological material (blood and tissue). Data were analyzed using Epi info 7 software. The subjects were predominantly male (95%

Indexed as

Laryngeal NeoplasmsSquamous Cell Carcinoma of Head and NeckTelomeraseFemaleGenotypeHumansLymphatic MetastasisMaleMiddle AgedTelomeraseTERT protein, humanETDA – ethylenediaminetetraacetic-acidG1 – well-differentiated squamous cell carcinomaG2 – moderately differentiated squamous cell carcinomaG3 – poorly differentiated squamous cell carcinomaHNC – head and neck cancerlaryngeal squamous cell carcinomaLSCC – laryngeal squamous cell carcinomaM – distant metastasisN – regional node metastasisPCR analysisReal-time-PCR – Real-time polymerase chain reactionSCC – squamous cell carcinomaTERC – telomere ARN componentTERT Rs2736100TERT – telomerase reverse transcriptaseTNM – tumor classification criteria-T (the primary tumor)UADT – upper aerodigestive tract

Identifiers

PMID36415512
PMCPMC9635231
OpenAlexW4310330421

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.