Evidence map›Paper›PMID 36415474›Full record

ArticleCureus2022

Proton Beam Therapy With Space-Making Surgery (Omental Plombage) for Oligorecurrent Liver Metastasis of Esophageal Adenocarcinoma.

Yojiro Ishikawa, Koji Morita, Hisashi Yamaguchi, Takahiro Kato, Motohisa Suzuki, Ichiro Seto, Masanori Machida, Kanako Takayama, Takuya Tominaga, Yoshiaki Takagawa and 4 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Yojiro IshikawaDepartment of Radiation Oncology, Southern Tohoku Proton Therapy Center, Koriyama, JPN.
Koji MoritaDepartment of Radiation Oncology, Southern Tohoku Proton Therapy Center, Koriyama, JPN.
Hisashi YamaguchiDepartment of Radiation Oncology, Southern Tohoku Proton Therapy Center, Koriyama, JPN.
Takahiro KatoDepartment of Radiation Physics and Technology, Southern Tohoku Proton Therapy Center, Koriyama, JPN.
Motohisa SuzukiDepartment of Radiation Oncology, Southern Tohoku Proton Therapy Center, Koriyama, JPN.
Ichiro SetoDepartment of Radiation Oncology, Southern Tohoku Proton Therapy Center, Koriyama, JPN.
Masanori MachidaDepartment of Radiation Oncology, Southern Tohoku Proton Therapy Center, Koriyama, JPN.
Kanako TakayamaDepartment of Radiation Oncology, Southern Tohoku Proton Therapy Center, Koriyama, JPN.
Takuya TominagaDepartment of Radiation Oncology, Southern Tohoku Proton Therapy Center, Koriyama, JPN.
Yoshiaki TakagawaDepartment of Radiation Oncology, Southern Tohoku Proton Therapy Center, Koriyama, JPN.
Masanobu NakajimaFirst Department of Surgery, Dokkyo Medical University, Mibu, JPN.
Yasushi TeranishiDepartment of Surgery, Southern Tohoku General Hospital, Koriyama, JPN.
Yasuhiro KikuchiDepartment of Neurosurgery, Southern Tohoku Research Institute for Neuroscience, Southern Tohoku General Hospital, Koriyama, JPN.
Masao MurakamiDepartment of Radiation Oncology, Southern Tohoku Proton Therapy Center, Koriyama, JPN.
Southern Tohoku General Hospital · JPProton (Malaysia) · MYDokkyo Medical University · JPTohoku Medical and Pharmaceutical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proton beam therapy (PBT) with space-making surgery has been used recently; however, its effectiveness for recurrent esophageal cancer (EC) is unclear. We herein report an unusual case of successful PBT with space-making surgery (omental plombage) for recurrent liver metastasis after EC surgery. A 58-year-old Japanese man underwent proximal gastrectomy for esophagogastric (EG) junction cancer seven months before presentation to our hospital. Microscopic findings after the surgery showed that the tumor was adenocarcinoma of the EG junction (pT1N0M0, stage I). Seven months after the proximal gastrectomy, liver metastases in S6 and S8 were revealed by positron emission tomography-computed tomography. Initial PBT was performed for those two liver metastases, and complete response (CR) was obtained for both liver metastases. Recurrence of liver metastasis in S2 was found eight months after the first PBT, and CR was achieved by chemotherapy. However, new liver metastasis recurred in S2. Considering the effects of radiation exposure on the surrounding gastrointestinal organs, we performed space-making surgery to place the omentum around the liver metastasis. We were able to complete the second PBT for the liver metastasis with 72.6 Gy relative biological effectiveness in 22 fractions. After the second PBT, the patient survived for seven years without recurrence. PBT with space-making surgery (omental plombage) for recurrent liver metastasis after EC surgery is considered to be a therapeutic option.

Indexed as

esophageal adenocarcinomaliver metastasisoligometastasisproton beam radiotherapyspace-making surgery

Identifiers

PMID36415474
PMCPMC9674453
OpenAlexW4309493251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.