Evidence map›Paper›PMID 36415233›Full record

ArticlePakistan journal of medical sciences

Analysis on efficacy of compound dextran combined with atorvastatin calcium in patients with CVS caused by SAH based on TCD blood flow indexes.

Yu Zhang, Feifan Ma, Ning Gan, Fei Su, Zhaoyan Song

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yu ZhangYu Zhang, Department of Neurosurgery, Baoding No.1 Central Hospital, Baoding, 071000, Hebei, China.
Feifan MaFeifan Ma, Department of Cardiac Intensive Care, Baoding No.1 Central Hospital, Baoding, 071000, Hebei, China.
Ning GanNing Gan, Department of Neurosurgery, Baoding No.1 Central Hospital, Baoding, 071000, Hebei, China.
Fei SuFei Su, Department of Neurosurgery, Baoding No.1 Central Hospital, Baoding, 071000, Hebei, China.
Zhaoyan SongZhaoyan Song, Department of Neurosurgery, Baoding No.1 Central Hospital, Baoding, 071000, Hebei, China.
Baoding People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To analyze the effects of compound dextran combined with atorvastatin calcium on blood flow indexes, peroxidase 2 (Prx2) and endothelin-1 (ET-1) in patients with cerebral vasospasm (CVS) caused by subarachnoid hemorrhage (SAH). Methods: One hundred patients with CVS caused by SAH treated in Baoding No.1 Central Hospital from January 2019 to December 2020 were divided into observation group and control group. The control group was treated with atorvastatin calcium tablets, while the observation group was additionally treated with compound dextran. The hospital stays, Glasgow Outcome Scale (GOS), hemoglobin (Hb) and hematocrit (Hct) levels before and five days after treatment were recorded. The hemodynamic parameters of the middle cerebral artery (MCA) and the serum levels of Prx2 and ET-1 were detected. Results: After treatment, GOS and Hct levels in the observation group were both higher than those in the control group ( Conclusions: Compound dextran combined with atorvastatin calcium can effectively enhance clinical efficacy, improve cerebral blood flow and reduce serum Prx2 and ET-1 levels in patients with CVS caused by SAH.

Indexed as

Atorvastatin calciumBlood flow indexesCerebral vasospasm caused by subarachnoid hemorrhageCompound dextranEndothelin-1Peroxidase 2

Identifiers

PMID36415233
PMCPMC9676581
OpenAlexW4296615259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.