Evidence map›Paper›PMID 36415167›Full record

ArticleThoracic cancer2023

Diagnosis of malignant pleural disease: Ultrasound as "a detective probe".

Gaetana Messina, Mary Bove, Giovanni Natale, Vincenzo Di Filippo, Giorgia Opromolla, Anna Rainone, Beatrice Leonardi, Mario Martone, Alfonso Fiorelli, Giovanni Vicidomini and 8 more

Open access · goldAbstract read
In one paragraph

Article in Thoracic cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  10. Lung Ultrasound and Pleural Artifacts: A Pictorial Review.Diagnostics (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Gaetana MessinaThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.ORCID https://orcid.org/0000-0001-5129-7201
Mary BoveThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.
Giovanni NataleThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.
Vincenzo Di FilippoThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.
Giorgia OpromollaThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.
Anna RainoneThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.
Beatrice LeonardiThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.
Mario MartoneThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.
Alfonso FiorelliThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.ORCID https://orcid.org/0000-0002-0628-613X
Giovanni VicidominiThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.
Mario SantiniThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.
Andrea RonchiPathology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.
Eva MassimillaOtorhinolaryngology Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.
Carminia Maria Della CorteOncology, Department of Precision Medicine, Università della Campania "L. Vanvitelli", Naples, Italy.
Mario PirozziOncology, Department of Precision Medicine, Università della Campania "L. Vanvitelli", Naples, Italy.
Marianna CaterinoOncology, Department of Precision Medicine, Università della Campania "L. Vanvitelli", Naples, Italy.
Fortunato CiardielloOncology, Department of Precision Medicine, Università della Campania "L. Vanvitelli", Naples, Italy.
Morena FasanoOncology, Department of Precision Medicine, Università della Campania "L. Vanvitelli", Naples, Italy.
University of Campania "Luigi Vanvitelli" · IT

Funding

Università degli Studi della Campania Luigi Vanvitelli
6 · The paper itself

Abstract

backgroundMalignant pleural mesothelioma (MPM) is an invasive, aggressive pleural tumor with a predominantly local spread. The objective of this study was to assess thoracic ultrasound (TUS) as an imaging modality with high sensitivity for the identification of malignant pleural involvement and in order to guide pleural biopsies.

methodsIn this retrospective single-center study between January 2018 and June 2022, 51 consecutive patients with impassable circumferential pleural thickening underwent TUS at the Thoracic Surgery Unit of the Vanvitelli University of Naples. Pleural biopsies were performed, and then large and multiple samples were sent to the pathological anatomy for histological examination.

resultsIn all patients who underwent ultrasound examination, we chose the optimal point of entry to perform pleural biopsies and selected the areas of greater thickening without pleural effusion. No patient had any complications. No drainage tubes were placed after the pleural biopsies and no pneumothorax was present during the following days of hospitalization. The patients were discharged on the second postoperative day.

conclusionWith TUS the precise pleural thickening localization, local infiltration, mass extent, its nature (solid, cystic or complex) and ultrasound features can be easily defined. Furthermore, ultrasound is more economical than computed tomography and avoids the risks associated with radiation. Thoracic ultrasound is an important component of the diagnostic procedure in detecting a safe entry site for biopsies of MPMs.

Indexed as

Mesothelioma, MalignantPleural DiseasesPleural NeoplasmsHumansPleuraRetrospective Studiesmalignant pleural mesotheliomapleural biopsiesprobethoracic ultrasound

Identifiers

PMID36415167
PMCPMC9870740
OpenAlexW4309707583

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.