ArticleInternational journal of methods in psychiatric research2023
Clinical subtyping using community detection: Limited utility?
Article in International journal of methods in psychiatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Reproducible Temperament Profiles in Adolescents With Attention-Deficit/Hyperactivity Disorder Prospectively Predict Clinical Outcomes.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- [Formula: see text] Data-driven profiles of behavior in pediatric medical disorders.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2026Article
- Cross-cultural variations in executive function impairments among children with attention deficit/hyperactivity disorder.JCPP advances · 2026Article
- Salience network segregation and symptom profiles in psychosis risk subgroups among youth and early adults.Schizophrenia (Heidelberg, Germany) · 2025Article
- Finding Similarities in Differences Between Autistic Adults: Two Replicated Subgroups.Journal of autism and developmental disorders · 2024Article
- Transdiagnostic clustering and network analysis for questionnaire-based symptom profiling and drug recommendation in the UK Biobank and a Korean cohort.Scientific reports · 2024Article
- Clinical subtyping using community detection: Limited utility?International journal of methods in psychiatric research · 2023Article
- Transdiagnostic profiles of behaviour and communication relate to academic and socioemotional functioning and neural white matter organisation.Journal of child psychology and psychiatry, and allied disciplines · 2023Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo discover psychiatric subtypes, researchers are adopting a method called community detection. This method was not subjected to the same scrutiny in the psychiatric literature as traditional clustering methods. Furthermore, many community detection algorithms have been developed without psychiatric sample sizes and variable numbers in mind. We aim to provide clarity to researchers on the utility of this method.
methodsWe provide an introduction to community detection algorithms, specifically describing the crucial differences between correlation-based and distance-based community detection. We compare community detection results to results of traditional methods in a simulation study representing typical psychiatry settings, using three conceptualizations of how subtypes might differ.
resultsWe discovered that the number of recovered subgroups was often incorrect with several community detection algorithms. Correlation-based community detection fared better than distance-based community detection, and performed relatively well with smaller sample sizes. Latent profile analysis was more consistent in recovering subtypes. Whether methods were successful depended on how differences were introduced.
conclusionsTraditional methods like latent profile analysis remain reasonable choices. Furthermore, results depend on assumptions and theoretical choices underlying subtyping analyses, which researchers need to consider before drawing conclusions on subtypes. Employing multiple subtyping methods to establish method dependency is recommended.
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