Evidence map›Paper›PMID 36414999›Full record

ArticleAntimicrobial resistance and infection control2022

Success rates of MRSA decolonization and factors associated with failure.

Wing-Kee Yiek, Mirjam Tromp, Riet Strik-Albers, Koen van Aerde, Nannet van der Geest-Blankert, Heiman F L Wertheim, Corianne Meijer, Alma Tostmann, Chantal P Bleeker-Rovers

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Methicillin-ResistantMicroorganisms · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Wing-Kee YiekDepartment of Internal Medicine, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, P O Box 9101, 6500 HB, Nijmegen, The Netherlands. Wingkee.Yiek@radboudumc.nl.
Mirjam TrompDepartment of Internal Medicine, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, P O Box 9101, 6500 HB, Nijmegen, The Netherlands.
Riet Strik-AlbersDepartment of Paediatric Infectious Disease and Immunology, Radboud University Medical Center, Radboudumc Institute for Molecular Life Sciences, Radboudumc Amalia Children's Hospital, Nijmegen, The Netherlands.
Koen van AerdeDepartment of Paediatric Infectious Disease and Immunology, Radboud University Medical Center, Radboudumc Institute for Molecular Life Sciences, Radboudumc Amalia Children's Hospital, Nijmegen, The Netherlands.
Nannet van der Geest-BlankertDepartment of Occupational Health, Radboud University Medical Center, Nijmegen, The Netherlands.
Heiman F L WertheimDepartment of Medical Microbiology, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Corianne MeijerDepartment of Medical Microbiology, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Alma TostmannDepartment of Medical Microbiology, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Chantal P Bleeker-RoversDepartment of Internal Medicine, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, P O Box 9101, 6500 HB, Nijmegen, The Netherlands. Chantal.bleeker-rovers@radboudumc.nl.
Radboud University Nijmegen · NLRadboud University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe evaluated the success rate of MRSA decolonization directly after treatment and after one year in patients who were treated at the outpatient MRSA clinic of a large university medical centre to identify potential contributing factors to treatment success and failure.

methodsData from November 1, 2013 to August 1, 2020 were used. Only patients who had undergone complete MRSA decolonization were included. Risk factors for MRSA treatment failure were identified using a multivariable logistic regression model.

resultsIn total, 127 MRSA carriers were included: 7 had uncomplicated carriage, 91 had complicated carriage, and 29 patients had complicated carriage in combination with an infection. In complicated carriers and complicated carriers with an infection final treatment was successful in 75.0%. Risk factors for initial treatment failure included having one or more comorbidities and not testing the household members. Risk factors for final treatment failure were living in a refugee centre, being of younger age (0-17 years), and having one or more comorbidities.

conclusionsThe results of this study indicate that patients with a refugee status and children treated at the paediatric clinic have a higher risk of MRSA decolonisation treatment failure. For this reason, it might be useful to revise decolonization strategies for these subgroups and to refer these patients to specialized outpatient clinics in order to achieve higher treatment success rates.

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAdolescentCarrier StateChildChild, PreschoolHumansInfantInfant, NewbornTreatment FailureTreatment OutcomeColonizationDecolonizationMRSATreatment success

Identifiers

PMID36414999
PMCPMC9682637
OpenAlexW4309673516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.