Evidence map›Paper›PMID 36414874›Full record

ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2023

Aetiology of long bone chronic osteomyelitis: an analysis of the current situation in one region in Egypt.

Ahmed Elsheikh, Akram Hashish, Mai Kamal, Sayed El-Mohammadi, Yasser Ismael

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In one paragraph

Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ahmed ElsheikhOrthopaedic Surgery Department, Faculty of Medicine, Benha University, Fareed Nada Street, Benha, 13511, Egypt. Ahmed.elsheikh@fmed.bu.edu.eg.ORCID http://orcid.org/0000-0001-5814-6684
Akram HashishOrthopaedic Surgery Department, Red Crescent Hospital, Cairo, Egypt.
Mai KamalClinical Pathology Department, Faculty of Medicine, Benha University, Benha, Egypt.
Sayed El-MohammadiOrthopaedic Surgery Department, Faculty of Medicine, Benha University, Fareed Nada Street, Benha, 13511, Egypt.
Yasser IsmaelClinical Pathology Department, Faculty of Medicine, Benha University, Benha, Egypt.
Benha University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic osteomyelitis (COM) is a devastating infection requiring a multidisciplinary approach, including radiology, microbiology, pathology, and orthopaedic surgery to treat. The present study analysed the bacterial profile causing chronic osteomyelitis and their antibiogram in our region. PATIENTS AND 

methodsThis prospective study was done on a consecutive group of patients who underwent surgical debridement for long bone COM. Three to six deep tissue samples were collected during the index debridement for microbiology and one sample for histopathology. Antimicrobial sensitivity testing used an automated bacterial identification system. Gram stain was used to identify the bacteria type from its size, shape, and arrangement of bacterial growth.

resultsIntra-operative deep tissue and bone specimens accurately identified causative bacteria in 84.8% of patients. Gram-ve bacilli (GNB) were the most common causative organisms in 51.6% of all growing samples (36.4% isolated G-ve and 15.2% mixed with G + ve). Thirty-three patients (30 males/three females) were included; the mean age at index debridement surgery was 37.1 years. Half of the cohort had no metalwork. The aetiology of COM was post-operative infection in half of the patients.

conclusionThere may be concerning features in our patients' aetiologies and causative organisms; closed fractures turn into COM postoperatively, several unsuccessful attempts, delayed index debridement, and more GNB. Plans need to be applied to break the cycle and improve outcomes.

Indexed as

Anti-Bacterial AgentsOsteomyelitisAdultBacteriaDebridementEgyptFemaleHumansMaleProspective StudiesAnti-Bacterial AgentsGram-negative bacilliMethicillin-resistantMultidrug-resistantOsteomyelitisPolymicrobialStaphylococcus aureus

Identifiers

PMID36414874
PMCPMC10036446
OpenAlexW4309646618

What OpenQuestion holds

Textfull text, public
LicenceCC BY
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.