Evidence map›Paper›PMID 36414772›Full record

ArticleEJNMMI physics2022

Deep progressive learning achieves whole-body low-dose

Taisong Wang, Wenli Qiao, Ying Wang, Jingyi Wang, Yang Lv, Yun Dong, Zheng Qian, Yan Xing, Jinhua Zhao

Abstract read
In one paragraph

Article in EJNMMI physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. EnhancingCancer imaging : the official publication of the International Cancer Imaging Society · 2025
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  12. Comparison ofEJNMMI physics · 2025
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  14. Expert consensus on workflow of PET/CT with long axial field-of-view.European journal of nuclear medicine and molecular imaging · 2025
    Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Taisong Wang *Department of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, No. 100 Haining Road, Shanghai, 200080, People's Republic of China.
Wenli Qiao *Department of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, No. 100 Haining Road, Shanghai, 200080, People's Republic of China.
Ying WangUnited Imaging Healthcare, Shanghai, People's Republic of China.
Jingyi WangUnited Imaging Healthcare, Shanghai, People's Republic of China.
Yang LvUnited Imaging Healthcare, Shanghai, People's Republic of China.
Yun DongUnited Imaging Healthcare, Shanghai, People's Republic of China.
Zheng QianUnited Imaging Healthcare, Shanghai, People's Republic of China.
Yan XingDepartment of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, No. 100 Haining Road, Shanghai, 200080, People's Republic of China. xy.1@163.com.
Jinhua ZhaoDepartment of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, No. 100 Haining Road, Shanghai, 200080, People's Republic of China. zhaojinhua1963@126.com.ORCID http://orcid.org/0000-0002-8867-7985

Funding

National Natural Science Foundation of China 81971647National Natural Science Foundation of China 82171978Shanghai Shen Kang Hospital Development Center SHDC2020CR2057B
6 · The paper itself

Abstract

objectivesTo validate a total-body PET-guided deep progressive learning reconstruction method (DPR) for low-dose

methodsList-mode data from the retrospective study (n = 26) were rebinned into short-duration scans and reconstructed with DPR. The standard uptake value (SUV) and tumor-to-liver ratio (TLR) in lesions and coefficient of variation (COV) in the liver in the DPR images were compared to the reference (OSEM images with full-duration data). In the prospective study, another 41 patients were injected with 1/3 of the activity based on the retrospective results. The DPR images (DPR_1/3(p)) were generated and compared with the reference (OSEM images with extended acquisition time). The SUV and COV were evaluated in three selected organs: liver, blood pool and muscle. Quantitative analyses were performed with lesion SUV and TLR, furthermore on small lesions (≤ 10 mm in diameter). Additionally, a 5-point Likert scale visual analysis was performed on the following perspectives: contrast, noise and diagnostic confidence.

resultsIn the retrospective study, the DPR with one-third duration can maintain the image quality as the reference. In the prospective study, good agreement among the SUVs was observed in all selected organs. The quantitative results showed that there was no significant difference in COV between the DPR_1/3(p) group and the reference, while the visual analysis showed no significant differences in image contrast, noise and diagnostic confidence. The lesion SUVs and TLRs in the DPR_1/3(p) group were significantly enhanced compared with the reference, even for small lesions.

conclusionsThe proposed DPR method can reduce the administered activity of

Indexed as

Deep progressive learningImage qualityLow dosePET

Identifiers

PMID36414772
PMCPMC9681960

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.