ArticleScientific reports2022
Chronic low back pain and its impact on physical function, mental health, and health-related quality of life: a cross-sectional study in Singapore.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07522021 (Effects of Daytime and Evening Rehabilitation Programs on Sleep Quality and Daytime Sleepiness in Patients With Lumbar Disc Herniation at High Risk for Obstructive Sleep Apnea), which is not on this map. Cited by 48 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Daytime and Evening Rehabilitation Programs on Sleep Quality and Daytime Sleepiness in Patients With Lumbar Disc Herniation at High Risk for Obstructive Sleep Apnea: A Randomized Controlled Trial
Who cites it
48 citing papers in PubMed, 5 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- The association between trunk flexion and low back pain in blue-collar workers: A systematic review.Work (Reading, Mass.) · 2026Pooled it
- Prevalence of chronic pain in the general population: A systematic review and meta-analysis.The Indian journal of medical research · 2026Pooled it
- Is yoga more beneficial than exercise-based interventions for patients with chronic low back pain? A systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- A Systematic Review of Regenerative Medicine Therapies for Axial Spine Pain of Facet Joint Origin.Current pain and headache reports · 2025Pooled it
- Effectiveness and safety of ultrasound-guided needle-knife therapy for patients with spinal pain disorders: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Experiences of Rehabilitation Professionals in Guiding Rehabilitation for People with Persistent Spinal Pain Syndrome Type 2: A Qualitative Study.Journal of occupational rehabilitation · 2026Article
- Prevalence and competing risk of psychiatric comorbidities in chronic low back pain by age group.Pain reports · 2026Article
- Association Between Body Composition, Muscle-to-Weight Ratio, and Functional Disability in Patients with Chronic Non-Specific Low Back Pain: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Comparative analysis of oblique lumbar interbody fusion and posterior lumbar interbody fusion for L5-S1 level: clinical and radiological outcomes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Differences in Depression and Anxiety, Quality of Life and Quality of Sleep Between Neuropathic and Nociceptive Patients with Chronic Low Back Pain: A Comparative, Multi-Center, Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Intradiscal mesenchymal stem cell therapy for degenerative disc disease: a systematic review and meta-analysis of randomized trials.Asian spine journal · 2026Review
- Low back pain, quality of life, and functional disability among drivers and nurses working in home healthcare services: a cross-sectional study.BMC nursing · 2026Article
- Changes in social health among older adults: a random intercept latent transition analysis from China.BMC geriatrics · 2026Article
- The relationship between treatment methods and depressive mood in patients with low back pain: a cross-sectional study.BMC musculoskeletal disorders · 2026Article
- Article
- A Longitudinal Study of Coping Strategies and Differences by Sex in Patients with Chronic Low Back Pain.Journal of clinical medicine · 2026Article
- Receiving preferred treatments may improve low back pain outcomes: a non-randomized comparative study.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Association between pain, physical performance, and kinesiophobia in older women with low back pain: A cross-sectional study.PloS one · 2026Article
- Sex-related associations between psychoemotional factors and health-related quality of life in patients with chronic low back pain.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Physical function, daily activities, and spinal pain in the elderly: A cross-sectional study.PloS one · 2026Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic low back pain, defined as low back pain lasting more than 3 months, is a globally prevalent health problem with significantly high medical and economic burden on individuals and the society. This study aimed to estimate the prevalence of chronic low back pain and examine its association with health outcomes including physical function, mental health, and quality of life among adult population in Singapore. Cross-sectional secondary data analysis was performed using baseline data of the 1941 adults (mean age: 52.6 years, range: 21-97 years) from a representative population health survey conducted in the Central region of Singapore. Those with self-reported chronic low back pain in past six months were identified. The Late-Life Function and Disability Instrument, Patient Health Questionnaire-9, and EQ-5D-5L were used to measure physical function and limitation, mental health, and health-related quality of life, respectively. Generalized Linear Regressions were used to examine the association of chronic low back pain with physical function, limitation, depressive symptoms, and health-related quality of life. There were 8.1% (n = 180) participants reporting having chronic low back pain in past six months, among whom 80.5% sought treatments at either primary care, specialist outpatient, or Traditional Chinese Medicine clinics. Individuals with chronic low back pain reported poorer physical function, more limitations in performing major life tasks and social activities, more depressive symptoms, and lower health-related quality of life (all p < 0.01), even after adjusting for socio-demographics, lifestyle factors, and number of morbidities. The prevalence of chronic low back pain was 8.1% among the study population. Chronic low back pain was associated with poorer physical function, more limitations and depressive symptoms, and lower health-related quality of life. The findings highlight the significant impact of chronic low back pain on physical function and limitation, mental health, and health-related quality of life in a general population. Increased awareness on prevention, early and proper management of low back pain, and rehabilitation policies are required to better tackle the burden of low back pain at the population level.
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