Evidence map›Paper›PMID 36414657›Full record

ArticleScientific reports2022

Magnetic resonance imaging texture analysis to differentiate ameloblastoma from odontogenic keratocyst.

João Pedro Perez Gomes, Celso Massahiro Ogawa, Rafael V Silveira, Gabriela Castellano, Catharina Simioni De Rosa, Clarissa Lin Yasuda, André Caroli Rocha, Bengt Hasseus, Kaan Orhan, Paulo Henrique Braz-Silva and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

João Pedro Perez Gomes *Department of Stomatology, Division of General Pathology, School of Dentistry, University of São Paulo (USP), São Paulo, SP, Brazil.
Celso Massahiro Ogawa *Postgraduate Program in Dentistry, Cruzeiro Do Sul University (UNICSUL), São Paulo, SP, Brazil.
Rafael V SilveiraInstitute of Physics Gleb Wataghin, University of Campinas (UNICAMP), Campinas, SP, Brazil.
Gabriela CastellanoInstitute of Physics Gleb Wataghin, University of Campinas (UNICAMP), Campinas, SP, Brazil.
Catharina Simioni De RosaDepartment of Stomatology, Division of General Pathology, School of Dentistry, University of São Paulo (USP), São Paulo, SP, Brazil.
Clarissa Lin YasudaBrazilian Institute of Neuroscience and Neurotechnology (BRAINN), Campinas, SP, Brazil.
André Caroli RochaDivision of Dentistry, Clinics Hospital of School of Medicine, USP, São Paulo, SP, Brazil.
Bengt HasseusDepartment of Oral Medicine and Pathology, Institute of Odontology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Kaan OrhanDepartment of Dentomaxillofacial Radiology, Faculty of Dentistry, Ankara University, Ankara, Turkey.
Paulo Henrique Braz-SilvaDepartment of Stomatology, Division of General Pathology, School of Dentistry, University of São Paulo (USP), São Paulo, SP, Brazil. pbraz@usp.br.
Andre Luiz Ferreira CostaPostgraduate Program in Dentistry, Cruzeiro Do Sul University (UNICSUL), São Paulo, SP, Brazil.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/07559-3
6 · The paper itself

Abstract

The differentiation between ameloblastoma (AB) and odontogenic keratocyst (OKC) is essential for the formulation of the surgical plan, especially considering the biological behavior of these two pathological entities. Therefore, developing means to increase the accuracy of the diagnostic process is extremely important for a safe treatment. The aim of this study was to use magnetic resonance imaging (MRI) based on texture analysis (TA) as an aid in differentiating AB from OKC. This study comprised 18 patients; eight patients with AB and ten with OKC. All diagnoses were determined through incisional biopsy and later through histological examination of the surgical specimen. MRI was performed using a 3 T scanner with a neurovascular coil according to a specific protocol. All images were exported to segmentation software in which the volume of interest (VOI) was determined by a radiologist, who was blind to the histopathological results. Next, the textural parameters were computed by using the MATLAB software. Spearman's correlation coefficient was used to assess the correlation between texture parameters and the selected variables. Differences in TA parameters were compared between AB and OKC by using the Mann-Whitney test. Mann-Whitney test showed a statistically significant difference between AB and OKC for the parameters entropy (P = 0.033) and sum average (P = 0.033). MRI texture analysis has the potential to discriminate between AB and OKC as a noninvasive method. MRI texture analysis can be an additional tool to differentiate ameloblastoma from odontogenic keratocyst.

Indexed as

AmeloblastomaOdontogenic CystsOdontogenic TumorsHumansMagnetic Resonance Imaging

Identifiers

PMID36414657
PMCPMC9681845

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.