ArticleNature communications2022
Ancient oral microbiomes support gradual Neolithic dietary shifts towards agriculture.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Lifestyle Impacts the Oral Microbiome of Classical and Post-Classical Societies in Italy.American journal of biological anthropology · 2026Article
- Ancient Species Diversity and Niche Adaptation in Tannerella and Porphyromonas Revealed Through Pangenomics.Genome biology and evolution · 2026Article
- Review
- Recent Microbial Evolutionary Insights From Metagenomics.Genome biology and evolution · 2026Review
- Article
- Diet-Oral Microbiota Interactions and Salivary Biomarkers of Nutritional Health: A Narrative Review.Nutrients · 2026Review
- Health and lifestyle in the Iron Age Italian community of Pontecagnano (Campania, Italy, 7th-6th century BCE).PloS one · 2026Article
- Effects of silver nanoparticle coating on peri-implant mucosa and microbiome.International journal of implant dentistry · 2025Article
- Wet Lab Protocols Matter: Choice of DNA Extraction and Library Preparation Protocols Bias Ancient Oral Microbiome Recovery.Molecular ecology resources · 2025Article
- Host Traits Impact the Outcome of Metagenomic Library Preparation From Dental Calculus Samples Across Diverse Mammals.Molecular ecology resources · 2025Article
- Ancient DNA and biomarkers from artefacts: insights into technology and cultural practices in Neolithic Europe.Proceedings. Biological sciences · 2025Article
- Ancient Microbiomes as Mirrored by DNA Extracted From Century-Old Herbarium Plants and Associated Soil.Molecular ecology resources · 2025Article
- [Archaeological Research on Periodontal Disease].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Review
- Article
- Exploring the potential of dental calculus to shed light on past human migrations in Oceania.Nature communications · 2024Article
- A systematic framework for understanding the microbiome in human health and disease: from basic principles to clinical translation.Signal transduction and targeted therapy · 2024Review
- Longitudinal Microbiome Changes in Supragingival Biofilm Transcriptomes Induced by Orthodontics.JDR clinical and translational research · 2024Article
- The IL-33/ST2 axis is protective against acute inflammation during the course of periodontitis.Nature communications · 2024Article
- Direct evidence of plant consumption in Neolithic Eastern Sudan from dental calculus analysis.Scientific reports · 2024Article
- Paleomicrobiology: Tracking the past microbial life from single species to entire microbial communities.Microbial biotechnology · 2024Review
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Authors and funding
22 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human microbiome has recently become a valuable source of information about host life and health. To date little is known about how it may have evolved during key phases along our history, such as the Neolithic transition towards agriculture. Here, we shed light on the evolution experienced by the oral microbiome during this transition, comparing Palaeolithic hunter-gatherers with Neolithic and Copper Age farmers that populated a same restricted area in Italy. We integrate the analysis of 76 dental calculus oral microbiomes with the dietary information derived from the identification of embedded plant remains. We detect a stronger deviation from the hunter-gatherer microbiome composition in the last part of the Neolithic, while to a lesser extent in the early phases of the transition. Our findings demonstrate that the introduction of agriculture affected host microbiome, supporting the hypothesis of a gradual transition within the investigated populations.
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