Evidence map›Paper›PMID 36414481›Full record

ReviewTrends in genetics : TIG2023

Technological advances in mosquito olfaction neurogenetics.

Iliano V Coutinho-Abreu, Omar S Akbari

Open access · greenAbstract readReview
In one paragraph

Review in Trends in genetics : TIG, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. The auditory efferent system in mosquitoes.Frontiers in cell and developmental biology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Iliano V Coutinho-AbreuSchool of Biological Sciences, Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Omar S AkbariSchool of Biological Sciences, Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: oakbari@ucsd.edu.
University of California San Diego · US

Funding

The olfactory basis of locating nectar sugar sources in Aedes aegypti mosquitoesR01AI148300 · NIAID · UNIVERSITY OF WASHINGTON · PI Omar Sultan Akbari, Ronald Jason Pitts · 2021 to 2026
$4.1M
Olfactory modulation of color vision and behavior in mosquitoesR01AI175152 · NIAID · UNIVERSITY OF WASHINGTON · PI Omar Sultan Akbari, Jeffrey A Riffell · 2023 to 2026
$3.2M
Precision guided SIT for the control of vector-borne diseaseR01AI151004 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AKBARI, OMAR SULTAN · 2020 to 2024
$2.3M
NIAID NIH HHS R01 AI148300NIAID NIH HHS R01 AI151004NIAID NIH HHS R01 AI175152
6 · The paper itself

Abstract

Gene-editing technologies have revolutionized the field of mosquito sensory biology. These technologies have been used to knock in reporter genes in-frame with neuronal genes and tag specific mosquito neurons to detect their activities using binary expression systems. Despite these advances, novel tools still need to be developed to elucidate the transmission of olfactory signals from the periphery to the brain. Here, we propose the development of a set of tools, including novel driver lines as well as sensors of neuromodulatory activities, which can advance our knowledge of how sensory input triggers behavioral outputs. This information can change our understanding of mosquito neurobiology and lead to the development of strategies for mosquito behavioral manipulation to reduce bites and disease transmission.

Indexed as

CulicidaeAnimalsGene EditingNeuronsSmellbinary expression systemsCRISPRGCaMPmosquitoolfactionsensors

Identifiers

PMID36414481
PMCPMC10564117
OpenAlexW4309419500

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.