Evidence map›Paper›PMID 36414376›Full record

ArticleAnnals of the rheumatic diseases2023

Taxonomy of fibroblasts and progenitors in the synovial joint at single-cell resolution.

Fraser L Collins, Anke J Roelofs, Rebecca A Symons, Karolina Kania, Ewan Campbell, Elaina S R Collie-Duguid, Anna H K Riemen, Susan M Clark, Cosimo De Bari

Open access · hybridAbstract read
In one paragraph

Article in Annals of the rheumatic diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Identification and characterization of POSTNJournal of orthopaedic translation · 2026
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  5. Mechanical Strain-Programmed SDC1Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Fraser L Collins *Arthritis and Regenerative Medicine Laboratory, Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, Aberdeen, UK c.debari@abdn.ac.uk fraser.collins@abdn.ac.uk.ORCID 0000-0002-1156-6873
Anke J Roelofs *Arthritis and Regenerative Medicine Laboratory, Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, Aberdeen, UK.ORCID 0000-0001-8993-1984
Rebecca A SymonsArthritis and Regenerative Medicine Laboratory, Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, Aberdeen, UK.ORCID 0000-0002-2811-7919
Karolina KaniaArthritis and Regenerative Medicine Laboratory, Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, Aberdeen, UK.
Ewan CampbellCentre for Genome-Enabled Biology and Medicine, University of Aberdeen, Aberdeen, UK.
Elaina S R Collie-DuguidCentre for Genome-Enabled Biology and Medicine, University of Aberdeen, Aberdeen, UK.
Anna H K RiemenArthritis and Regenerative Medicine Laboratory, Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, Aberdeen, UK.
Susan M ClarkArthritis and Regenerative Medicine Laboratory, Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, Aberdeen, UK.
Cosimo De BariArthritis and Regenerative Medicine Laboratory, Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, Aberdeen, UK c.debari@abdn.ac.uk fraser.collins@abdn.ac.uk.ORCID 0000-0002-5113-862X
University of Aberdeen · GB

Funding

Medical Research Council MR/L020211/1Versus Arthritis 20775Versus Arthritis 21156Versus Arthritis 21800
6 · The paper itself

Abstract

objectivesFibroblasts in synovium include fibroblast-like synoviocytes (FLS) in the lining and

methodsTo discriminate between

resultsIn steady state,

conclusionsOur findings blueprint a cell atlas of mouse synovial fibroblasts and progenitors in healthy and injured knees, and provide novel insights into the cellular and molecular principles governing the organisation and maintenance of adult synovial joints.

Indexed as

Receptor, Platelet-Derived Growth Factor alphaSynoviocytesAdultAnimalsFibroblastsHumansJointsMiceSynovial MembraneReceptor, Platelet-Derived Growth Factor alphaFibroblastsOsteoarthritis, KneeSynovitis

Identifiers

PMID36414376
PMCPMC9933170
OpenAlexW4309621463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.