Evidence map›Paper›PMID 36414261›Full record

ArticleThe British journal of ophthalmology2022

Argon laser photocoagulation for treatment of presumed trematode-induced granulomatous anterior uveitis in children.

Alahmady Hamad Alsmman, Abdelsalam Abdalla, Mohammed Ezzeldawla, Elshimaa A Mateen Mossa, Mortada Abozaid

Open access · hybridAbstract readControlled Clinical Trial
In one paragraph

Article in The British journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Alahmady Hamad AlsmmanDepartment of Ophthalmology, Faculty of Medicine, Sohag University, Sohag, Egypt.ORCID 0000-0001-6436-5576
Abdelsalam AbdallaDepartment of Ophthalmology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Mohammed EzzeldawlaDepartment of Ophthalmology, Faculty of Medicine, Sohag University, Sohag, Egypt.
Elshimaa A Mateen MossaDepartment of Ophthalmology, Faculty of Medicine, Sohag University, Sohag, Egypt.ORCID 0000-0001-6989-7483
Mortada AbozaidDepartment of Ophthalmology, Faculty of Medicine, Sohag University, Sohag, Egypt mourtada_abdelaal@med.sohag.edu.eg.ORCID 0000-0002-0161-8035
Sohag University · EGAssiut University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsTo assess the safety and efficacy of argon laser photocoagulation as a new modality for the treatment of presumed trematode-induced granulomatous anterior uveitis (PTGAU) in children.

methodsForty-eight eyes of 48 children with PTGAU with pearl-like nodule(s) in the anterior chamber were included in this prospective non-randomised controlled clinical trial. The patients were divided into two groups: those in Group A (23 eyes) were treated with one session of argon laser applied to the anterior chamber nodules and those in Group B (25 eyes) received medical treatment in the form of topical steroid and cycloplegic eye drops with trans-septal triamcinolone injections. All cases were followed up for 3 months with measurement of visual acuity (VA), assessment of the anterior chamber reaction and measurement of the pearl-like nodule size.

resultsIn Group A, 22 eyes (95.65%) showed regression of the pearl-like nodules with resolution of the anterior chamber reaction (flare and cells) and improvement in visual acuity from 0.52±0.12 to 0.06±0.08 logMAR (p<0.001). Such improvement was maintained within the 3-month follow-up period. In Group B, 23 eyes (92%) showed initial regression of the granulomas, which was maintained in only 14 eyes (56%),with nine eyes experiencing recurrence after 3 months of follow-up.

conclusionArgon laser photocoagulation is a safe and effective novel treatment for PTGAU with pearl-like nodules in the anterior chamber in children. Larger studies with longer follow-up periods are needed to confirm these results.

Indexed as

TrematodaUveitis, AnteriorAnimalsArgonChildHumansLaser CoagulationLasersProspective StudiesArgonanterior chamberclinical trialinflammationTreatment lasers

Identifiers

PMID36414261
PMCPMC9685699
OpenAlexW3176724333

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.