Evidence map›Paper›PMID 36413704›Full record

ArticleAmerican journal of public health2023

Microrandomized Trials: Developing Just-in-Time Adaptive Interventions for Better Public Health.

Xueqing Liu, Nina Deliu, Bibhas Chakraborty

Registry-linked trialAbstract read
In one paragraph

Article in American journal of public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07746492 (A Digital Real-Time Support for Stress-Induced Smoking and Unhealthy Eating Among Gender and Sexual Minorities in Dhaka), which is not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07746492 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Digital Real-Time Support for Stress-Induced Smoking and Unhealthy Eating Among Gender and Sexual Minorities in Dhaka

TypeinterventionalSponsorInternational Centre for Diarrhoeal Disease Research, BangladeshRan2026 to 2027Enrolled115ConditionsTobacco Use, Electronic Cigarette Use, Emotional Eating, Stress, PsychologicalArmsJust-in-Time Adaptive Support Message
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xueqing LiuXueqing Liu is with the Centre for Quantitative Medicine, Duke-National University of Singapore (NUS) Medical School, Singapore. Nina Deliu is with the Medical Research Council Biostatistics Unit, University of Cambridge, UK, and the Department of Methods and Models for Economics, Territory and Finance, Sapienza University of Rome, Italy. Bibhas Chakraborty is with the Centre for Quantitative Medicine and Program in Health Services and Systems Research, Duke-NUS Medical School, Singapore; the Department of Statistics and Data Science, NUS, Singapore; and the Department of Biostatistics and Bioinformatics, Duke University, Durham, NC.
Nina DeliuXueqing Liu is with the Centre for Quantitative Medicine, Duke-National University of Singapore (NUS) Medical School, Singapore. Nina Deliu is with the Medical Research Council Biostatistics Unit, University of Cambridge, UK, and the Department of Methods and Models for Economics, Territory and Finance, Sapienza University of Rome, Italy. Bibhas Chakraborty is with the Centre for Quantitative Medicine and Program in Health Services and Systems Research, Duke-NUS Medical School, Singapore; the Department of Statistics and Data Science, NUS, Singapore; and the Department of Biostatistics and Bioinformatics, Duke University, Durham, NC.
Bibhas ChakrabortyXueqing Liu is with the Centre for Quantitative Medicine, Duke-National University of Singapore (NUS) Medical School, Singapore. Nina Deliu is with the Medical Research Council Biostatistics Unit, University of Cambridge, UK, and the Department of Methods and Models for Economics, Territory and Finance, Sapienza University of Rome, Italy. Bibhas Chakraborty is with the Centre for Quantitative Medicine and Program in Health Services and Systems Research, Duke-NUS Medical School, Singapore; the Department of Statistics and Data Science, NUS, Singapore; and the Department of Biostatistics and Bioinformatics, Duke University, Durham, NC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Just-in-time adaptive interventions (JITAIs) represent an intervention design that adapts the provision and type of support over time to an individual's changing status and contexts, intending to deliver the right support on the right occasion. As a novel strategy for delivering mobile health interventions, JITAIs have the potential to improve access to quality care in underserved communities and, thus, alleviate health disparities, a significant public health concern. Valid experimental designs and analysis methods are required to inform the development of JITAIs. Here, we briefly review the cutting-edge design of microrandomized trials (MRTs), covering both the classical MRT design and its outcome-adaptive counterpart. Associated statistical challenges related to the design and analysis of MRTs are also discussed. Two case studies are provided to illustrate the aforementioned concepts and designs throughout the article. We hope our work leads to better design and application of JITAIs, advancing public health research and practice. (

Indexed as

Public HealthTelemedicineHumansResearch Design

Identifiers

PMID36413704
PMCPMC9755932

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.